Common use of Change to Reported Matters Clause in Contracts

Change to Reported Matters. (1) In the case of a change in the trade name, representative, agent, signature, seal, location, or other matter reported to the Agent, of a Lender and the Borrower, a written notice shall be promptly given to the Agent. (2) In the case where a notice under this Agreement is delayed or does not arrive as a result of a failure to report under the preceding Item, it shall be deemed to have arrived at the time it could be expected to have arrived. Subordinated Syndicated Loan Agreement dated October 26, 2018, for Takeda Pharmaceutical Company Limited 43 Attachment 2 PRINCIPAL PAYMENT SCHEDULE, INTEREST PAYMENT DATE SCHEDULE 1. Principal Payment Schedule for Individual Loans Principal Payment Date Principal Payment Amount 60th anniversary of the Drawdown Date (Maturity Date) Initial loan drawdown amount(*) (*) The initial loan drawdown amount is the total amount of the Individual Loan disbursed by each of the Lenders under the Drawdown Notice relating to such loans. The allocation of payment amounts to each Lender on each Principal Payment Date is as set out below. Each Lender excluding Sumitomo Mitsui Banking Corporation Sumitomo Mitsui Banking Corporation Maturity Date For each Lender, the entire principal portion of its Outstanding Individual Loan Amount Subordinated Syndicated Loan Agreement dated October 26, 2018, for Takeda Pharmaceutical Company Limited 44 Attachment 3 [DATE] To: Sumitomo Mitsui Banking Corporation Inter-Market Settlement Department [ADDRESS] [NAME] [Registered Seal] DRAWDOWN NOTICE We refer to the Subordinated Syndicated Loan Agreement dated October 26, 2018 entered into by and between the Borrower and, inter alia, Sumitomo Mitsui Banking Corporation as the Agent (hereafter the “Agreement”. Defined terms used herein but not otherwise defined shall have the meanings ascribed to them in the Agreement.) for the initial Total Commitment Amount of ¥500,000,000,000 as of the execution date of the Agreement, and subject to the terms and conditions thereof, we wish to borrow loans on the terms set out below. We confirm that as of the date of the Drawdown Notice and presently on the Requested Drawdown Date set out below, each condition precedent prescribed in Article 2-2 of the Agreement relating to the Lending Obligations is fulfilled. Total Amount Yen Requested Drawdown Date [•] [•] , [•] (Day of the Week) Purpose of Funds Repayment of the debt borrowed pursuant to the SSTL on the Requested Drawdown Date With respect to the Individual Loans that are disbursed in accordance with this Drawdown Notice, the Principal Payment Date, Interest Payment Date and Principal Payment Amount and the handling of the Principal Payment Date and the Interest Payment Date in event such days falling on a bank holiday shall be as set out in the relevant provisions of the Agreement. Subordinated Syndicated Loan Agreement dated October 26, 2018, for Takeda Pharmaceutical Company Limited 45 Attachment 4 EXCLUSION OF ANTI-SOCIAL FORCES (1) Members of Organized Crime Groups, etc. (a) Organized Crime Groups (boryokudan) (an organization whose members (including members of member organizations) are suspected of supporting collective or habitual violent and unlawful conduct; the same shall apply hereinafter);

Change to Reported Matters. (1) In the case of a change in the trade name, representative, agent, signature, seal, location, or other matter reported to the Agent, of a Lender and the Borrower, a written notice shall be promptly given to the Agent. (2) In the case where a notice under this Agreement is delayed or does not arrive as a result of a failure to report under the preceding Item, it shall be deemed to have arrived at the time it could be expected to have arrived. Subordinated Syndicated Loan Agreement dated October 26, 2018, for Takeda Pharmaceutical Company Limited 43 Attachment 2 PRINCIPAL PAYMENT SCHEDULE, INTEREST PAYMENT DATE SCHEDULE 1. Principal Payment Schedule for Individual Loans Principal Payment Date Principal Payment Amount 60th anniversary of the Drawdown Date (Maturity Date) Initial loan drawdown amount(*) (*) The initial loan drawdown amount is the total amount of the Individual Loan disbursed by each of the Lenders under the Drawdown Notice relating to such loans. The allocation of payment amounts to each Lender on each Principal Payment Date is as set out below. Each Lender excluding Sumitomo Mitsui Banking Corporation Sumitomo Mitsui Banking Corporation Maturity Date For each Lender, the entire principal portion of its Outstanding Individual Loan Amount Subordinated Syndicated Loan Agreement dated October 26, 2018, for Takeda Pharmaceutical Company Limited 44 Attachment 3 [DATE] To: Sumitomo Mitsui Banking Corporation Inter-Market Settlement Department [ADDRESS] [NAME] [Registered Seal] DRAWDOWN NOTICE We refer to the Subordinated Syndicated Loan Agreement dated October 26, 2018 entered into by and between the Borrower and, inter alia, Sumitomo Mitsui Banking Corporation as the Agent (hereafter the “Agreement”. Defined terms used herein but not otherwise defined shall have the meanings ascribed to them in the Agreement.) for the initial Total Commitment Amount of ¥500,000,000,000 as of the execution date of the Agreement, and subject to the terms and conditions thereof, we wish to borrow loans on the terms set out below. We confirm that as of the date of the Drawdown Notice and presently on the Requested Drawdown Date set out below, each condition precedent prescribed in Article 2-2 of the Agreement relating to the Lending Obligations is fulfilled. Total Amount Yen Requested Drawdown Date [•] [•] , [•] (Day of the Week) Purpose of Funds Repayment of the debt borrowed pursuant to the SSTL on the Requested Drawdown Date With respect to the Individual Loans that are disbursed in accordance with this Drawdown Notice, the Principal Payment Date, Interest Payment Date and Principal Payment Amount and the handling of the Principal Payment Date and the Interest Payment Date in event such days falling on a bank holiday shall be as set out in the relevant provisions of the Agreement. Subordinated Syndicated Loan Agreement dated October 26, 2018, for Takeda Pharmaceutical Company Limited 45 Attachment 4 EXCLUSION OF ANTI-SOCIAL FORCESLimited (1) Members of Organized Crime Groups, etc. (a) Organized Crime Groups (boryokudan) (an organization whose members (including members of member organizations) are suspected of supporting collective or habitual violent and unlawful conduct; the same shall apply hereinafter);