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End User Agreement. This publication is distributed under the terms of Article 25fa of the Dutch Copyright Act. This article entitles the maker of a short scientific work funded either wholly or partially by Dutch public funds to make that work publicly available for no consideration following a reasonable period of time after the work was first published, provided that clear reference is made to the source of the first publication of the work. Research outputs of researchers employed by Dutch Universities that comply with the legal requirements of Article 25fa of the Dutch Copyright Act, are distributed online and free of cost or other barriers in institutional repositories. Research outputs are distributed six months after their first online publication in the original published version and with proper attribution to the source of the original publication. You are permitted to download and use the publication for personal purposes. All rights remain with the author(s) and/or copyrights owner(s) of this work. Any use of the publication other than authorised under this licence or copyright law is prohibited. If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the University Library know, stating your reasons. In case of a legitimate complaint, the University Library will, as a precaution, make the material inaccessible and/or remove it from the website. Please contact the University Library through email: ▇▇▇▇▇▇▇▇▇@▇▇▇.▇▇.▇▇. You will be contacted as soon as possible. University Library Radboud University Published on 27 June 2013. Downloaded by Radboud University Nijmegen on 9/5/2022 10:50:53 AM. Soft Matter PAPER Cite this: Soft Matter, 2013, 9, 10493 Received 26th April 2013 Accepted 27th June 2013 DOI: 10.1039/c3sm51163d ▇▇▇.▇▇▇.▇▇▇/▇▇▇▇▇▇▇▇▇▇ Self-organization of the bacterial cell-division protein FtsZ in confined environments† ▇▇▇▇▇ ▇▇▇▇▇▇▇▇,‡a Begon~a ▇▇▇▇▇▇▇▇▇▇,‡b ▇▇▇▇▇▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇,a Esra ▇▇ ▇▇▇▇▇▇,a ▇▇▇▇▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇▇▇▇▇▇,a Germa´n ▇▇▇▇▇§*b and ▇▇▇▇▇▇▇ ▇. ▇. ▇▇▇▇§*a We report a microfluidic approach to generate aqueous droplets in oil of different dimensionality, stabilized by a lipid monolayer, to systematically probe the polymerization of bacterial cell-division protein FtsZ into fibrous networks as a function of the concentrations of crowding agent, FtsZ, and GTP. FtsZ bundles confined in droplets were dynamic, and their distribution depended on the intrinsic properties of the system and restrictions imposed by the spatial boundaries.

End User Agreement. This publication is distributed under the terms of Article 25fa of the Dutch Copyright Act. This article entitles the maker of a short scientific work funded either wholly or partially by Dutch public funds to make that work publicly available for no consideration following a reasonable period of time after the work was first published, provided that clear reference is made to the source of the first publication of the work. Research outputs of researchers employed by Dutch Universities that comply with the legal requirements of Article 25fa of the Dutch Copyright Act, are distributed online and free of cost or other barriers in institutional repositories. Research outputs are distributed six months after their first online publication in the original published version and with proper attribution to the source of the original publication. You are permitted to download and use the publication for personal purposes. All rights remain with the author(s) and/or copyrights owner(s) of this work. Any use of the publication other than authorised under this licence or copyright law is prohibited. If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the University Library know, stating your reasons. In case of a legitimate complaint, the University Library will, as a precaution, make the material inaccessible and/or remove it from the website. Please contact the University Library through email: ▇▇▇▇▇▇▇▇▇@▇▇▇.▇▇.▇▇. You will be contacted as soon as possible. University Library Radboud University Published on 27 June 201305 January 2018. Downloaded by Radboud University Nijmegen on 9/5/2022 10:50:53 AM2/21/2020 3:54:43 PM. Soft Matter PCCP PAPER Cite this: Soft MatterPhys. Chem. Chem. Phys., 20132018, 920, 10493 4067 Received 26th April 2013 28th November 2017, Accepted 27th June 2013 5th January 2018 DOI: 10.1039/c3sm51163d c7cp07975c ▇▇▇.▇▇▇./▇▇▇▇ Guanidinium/ammonium competition and proton transfer in the interaction of the amino acid arginine with the tetracarboxylic 18-crown-6 ionophore† ▇▇▇▇ ▇▇▇▇´n ▇▇▇▇▇´s-▇▇▇▇▇▇▇▇▇▇ Self-organization of the bacterial cell-division protein FtsZ in confined environments† ▇, a ▇▇▇▇ ▇▇▇▇▇▇▇▇,‡a Begon~a ▇▇▇▇▇▇▇▇▇▇,‡b ▇▇▇▇▇▇▇▇▇▇ , b ▇▇▇ ▇▇▇▇▇▇▇▇,a Esra ▇▇ ▇▇▇▇▇▇,a ▇▇▇▇▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇▇▇▇▇▇,a Germa´n ▇▇▇▇▇§*b and ▇▇▇▇▇▇▇ ▇. ▇. Mart´▇▇▇▇§-▇▇▇▇ *a We report 3 The recognition of arginine plays a microfluidic approach central role in modern proteomics and genomics. Arginine is unique among natural amino acids due to generate aqueous droplets the high basicity of its guanidinium side chain, which sustains specific interactions and proton exchange biochemical processes. The search for suitable macrocyclic iono- phores constitutes a promising route towards the development of arginine receptors. This study evaluates the conformational features involved in oil the binding of different dimensionality, free arginine by the polyether macrocycle (18-crown-6)-tetracarboxylic acid. Infrared action vibrational spectroscopy and quantum- chemical computations are combined to characterize the complexes with net charges +1 and +2. The spectrum of the +1 complex can be explained in terms of a configuration predominantly stabilized by a lipid monolayer, to systematically probe robust bidentate coordination of guanidinium with a carboxylate group formed from the polymerization deprotonation of bacterial cell-division protein FtsZ into fibrous networks as a function one side group of the concentrations crown ether. The released proton is transferred to the amino terminus of crowding agentarginine, FtsZwhich then coordinates with the crown ether ring. In an alternative type of conformation, partly consistent with experiment, the amino terminus is neutral and GTPthe guanidinium group inserts into the crown ether cavity. FtsZ bundles confined in droplets were dynamicIn the +2 complexes, arginine is always doubly protonated and their distribution depended on the intrinsic properties most stable conformations are characterized by a tripodal coordination of the system and restrictions imposed by ammonium –NH + group of arginine with the spatial boundariesoxygen atoms of the macrocycle ring, while the interactions of the amino acid with the side carboxylic acid groups of the crown ether acquire a remarkable lesser role.

End User Agreement. This publication is distributed under the terms of Article 25fa of the Dutch Copyright Act. This article entitles the maker of a short scientific work funded either wholly or partially by Dutch public funds to make that work publicly available for no consideration following a reasonable period of time after the work was first published, provided that clear reference is made to the source of the first publication of the work. Research outputs of researchers employed by Dutch Universities that comply with the legal requirements of Article 25fa of the Dutch Copyright Act, are distributed online and free of cost or other barriers in institutional repositories. Research outputs are distributed six months after their first online publication in the original published version and with proper attribution to the source of the original publication. You are permitted to download and use the publication for personal purposes. All rights remain with the author(s) and/or copyrights owner(s) of this work. Any use of the publication other than authorised under this licence or copyright law is prohibited. If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the University Library know, stating your reasons. In case of a legitimate complaint, the University Library will, as a precaution, make the material inaccessible and/or remove it from the website. Please contact the University Library through email: ▇▇▇▇▇▇▇▇▇@▇▇▇.▇▇.▇▇. You will be contacted as soon as possible. University Library Radboud University Published on 27 June 2013. Downloaded by Radboud University Nijmegen on 9/5/2022 10:50:53 AM. Soft Matter PAPER Cite thisInternational Edition: Soft Matter, 2013, 9, 10493 Received 26th April 2013 Accepted 27th June 2013 DOI: 10.103910.1002/c3sm51163d anie.201808085 German Edition: DOI: 10.1002/ange.201808085 Nucleophilic versus Electrophilic Reactivity of Bioinspired Superoxido Nickel(II) Complexes ▇▇▇.▇▇▇.▇▇▇ ▇▇▇/▇▇+, ▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇+, ▇▇▇▇▇▇ ▇▇▇▇▇▇, ▇▇▇▇ ▇▇▇▇▇▇, ▇▇▇▇▇▇▇ ▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇ ▇▇▇▇▇, ▇▇▇▇ ▇▇▇▇▇▇▇▇▇▇ Self-organization of the bacterial cell-division protein FtsZ in confined environments† ▇▇, ▇▇▇▇▇▇ ▇▇▇▇▇▇▇▇,‡a Begon~a , ▇▇▇▇ ▇. ▇▇▇▇▇▇▇▇, ▇▇,‡b ▇▇▇▇▇▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇,a Esra ▇▇ ▇▇▇▇▇▇,a ▇▇▇▇▇▇* ▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇▇▇,* ▇▇▇,a Germa´n ▇▇▇▇▇§*b and ▇▇▇▇▇▇▇ ▇. ▇. ▇▇▇▇§▇,* and ▇▇▇▇▇▇ ▇▇▇*a We report a microfluidic approach to generate aqueous droplets in oil of different dimensionality, stabilized by a lipid monolayer, to systematically probe the polymerization of bacterial cell-division protein FtsZ into fibrous networks as a function of the concentrations of crowding agent, FtsZ, and GTP. FtsZ bundles confined in droplets were dynamic, and their distribution depended on the intrinsic properties of the system and restrictions imposed by the spatial boundaries.

End User Agreement. This publication is distributed under the terms of Article 25fa of the Dutch Copyright Act. This article entitles the maker of a short scientific work funded either wholly or partially by Dutch public funds to make that work publicly available for no consideration following a reasonable period of time after the work was first published, provided that clear reference is made to the source of the first publication of the work. Research outputs of researchers employed by Dutch Universities that comply with the legal requirements of Article 25fa of the Dutch Copyright Act, are distributed online and free of cost or other barriers in institutional repositories. Research outputs are distributed six months after their first online publication in the original published version and with proper attribution to the source of the original publication. You are permitted to download and use the publication for personal purposes. All rights remain with the author(s) and/or copyrights owner(s) of this work. Any use of the publication other than authorised under this licence or copyright law is prohibited. If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the University Library know, stating your reasons. In case of a legitimate complaint, the University Library will, as a precaution, make the material inaccessible and/or remove it from the website. Please contact the University Library through email: ▇▇▇▇▇▇▇▇▇@▇▇▇.▇▇.▇▇. You will be contacted as soon as possible. University Library Radboud University Published on 27 June 2013. Downloaded by Radboud University Nijmegen on 9/5/2022 10:50:53 AM. Soft Matter PAPER Cite this: Soft MatterTHz Electric Field-induced Second Harmonic Generation in Ferroelectric Thin Film BaSrTiO3 K. A. Grishunin1, 2013N. A. Ilyin1, 9N. E. Sherstyuk1, 10493 Received 26th April 2013 Accepted 27th June 2013 DOI: 10.1039/c3sm51163d ▇▇▇.▇▇▇.▇▇▇/▇▇▇▇▇▇▇▇▇▇ Self-organization of the bacterial cell-division protein FtsZ in confined environments† ▇▇▇▇▇ ▇▇▇▇▇▇▇▇,‡a Begon~a ▇▇▇▇▇▇▇▇▇▇,‡b ▇▇▇▇▇▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇,a Esra ▇▇ ▇▇▇▇▇▇,a ▇▇▇▇E. D. Mishina1, A. Kimel2, V. M. Mukhortov3, A. V. Ovchinnikov4, O. V. Chefonov4, and M. B. Agranat4 1MIREA, Moscow Technological University, ▇▇▇▇▇▇▇▇▇ ▇▇▇. ▇▇▇▇▇▇▇▇▇,a Germa´n ▇▇▇▇▇§*b and ▇, ▇▇▇▇▇▇ ▇. ▇. ▇▇▇▇§*a We report a microfluidic approach to generate aqueous droplets in oil ▇, ▇▇▇▇▇▇ 2Institute for Molecules and Materials, Radboud University Nijmegen, 6525 AJ, Nijmegen, The Netherlands 3Southern Scientific Center of different dimensionalityRussian Academy of Sciences, stabilized by a lipid monolayerChehova 41, to systematically probe the polymerization Rostov-on-Don 344006, Russia 4Joint Institute for High Temperatures of bacterial cell-division protein FtsZ into fibrous networks as a function Russian Academy of Sciences (JIHT) Izhorskayast. 13, Bd. 2, Moscow 125412, Russia Abstract— Strong modulation of the concentrations Second Harmonic Generation (SHG) signal by THz nearly single cycle pulse in ferroelectric thin film BaSrTiO3 was observed. As the employed THz pulses pumps the medium in the range of crowding agentphononic excitations, FtsZ, and GTPthe THz electric field induced ferro- electric polarization is due to the ionic contribution. FtsZ bundles confined The proposed model describes this effect in droplets were dynamic, and their distribution depended terms of electric polarization induced in the plane of the film. The net SHG signal responds to the THz excitation as if the THz pulse induces a 90-degrees switching of the polarization in parts of the sample on the intrinsic properties time scale of the system and restrictions imposed by period of the spatial boundariessoft mode. According to the proposed model, under action of the THz pulse the latter acquires an in-plane component up to 6% of the net polarization.

End User Agreement. This publication is distributed under the terms of Article 25fa of the Dutch Copyright Act. This article entitles the maker of a short scientific work funded either wholly or partially by Dutch public funds to make that work publicly available for no consideration following a reasonable period of time after the work was first published, provided that clear reference is made to the source of the first publication of the work. Research outputs of researchers employed by Dutch Universities that comply with the legal requirements of Article 25fa of the Dutch Copyright Act, are distributed online and free of cost or other barriers in institutional repositories. Research outputs are distributed six months after their first online publication in the original published version and with proper attribution to the source of the original publication. You are permitted to download and use the publication for personal purposes. All rights remain with the author(s) and/or copyrights owner(s) of this work. Any use of the publication other than authorised under this licence or copyright law is prohibited. If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the University Library know, stating your reasons. In case of a legitimate complaint, the University Library will, as a precaution, make the material inaccessible and/or remove it from the website. Please contact the University Library through email: ▇▇▇▇▇▇▇▇▇@▇▇▇.▇▇.▇▇. You will be contacted as soon as possible. University Library Radboud University Published on 27 June 2013. Downloaded by Radboud University Nijmegen on 9/5/2022 10:50:53 AM. Soft Matter PAPER Cite this: Soft Matter, 2013, 9, 10493 Received 26th April 2013 Accepted 27th June 2013 DOI: 10.1039/c3sm51163d Correspondence ▇▇▇▇ ▇. ▇▇ ▇.▇▇▇.▇▇▇/@▇▇▇▇▇▇▇.▇▇.▇▇ Received 3 September 2010 Revised 9 November 2010 Accepted 10 November 2010 Physiological role of the respiratory quinol oxidase in the anaerobic nitrite-reducing methanotroph ‘Candidatus Methylomirabilis oxyfera’ ▇▇▇▇ Self-organization of the bacterial cell-division protein FtsZ in confined environments† ▇. ▇▇,1 ▇▇▇▇▇ ▇▇ ▇▇▇▇▇,2 ▇▇▇▇ ▇. ▇▇▇ ▇▇▇▇▇▇▇▇,‡a Begon~a ▇▇▇▇▇▇▇▇▇▇,‡b ▇▇1 ▇▇▇▇▇▇▇▇ ▇▇▇ ▇▇. ▇▇▇▇▇▇,a Esra 13 ▇▇▇▇ ▇. ▇. Op den Camp,1 ▇▇▇ ▇. Keltjens,1 ▇▇▇▇ ▇. ▇,a . Jetten1,2 and Marc Strous1,3,4 1Department of Microbiology, Institute of Wetland and Water Research (IWWR), Radboud University Nijmegen, ▇▇▇▇▇▇▇▇▇▇▇▇▇ ▇▇▇, ▇▇▇▇ ▇▇ ▇▇▇▇▇▇▇▇, ▇▇▇ ▇▇▇▇▇▇▇▇▇,a Germa´n ▇▇ 2Department of Biotechnology, Delft University of Technology, ▇▇▇▇▇§*b and ▇▇▇▇▇▇▇ ▇. ▇. , ▇▇▇▇ ▇▇ ▇▇▇▇§*a We report a microfluidic approach to generate aqueous droplets in oil ▇, ▇▇▇ ▇▇▇▇▇▇▇▇▇▇▇ 3Max ▇▇▇▇▇▇ Institute for Marine Microbiology, ▇▇▇▇▇▇▇▇▇▇. ▇, ▇-▇▇▇▇▇ ▇▇▇▇▇▇, ▇▇▇▇▇▇▇ 4Centre for Biotechnology, University of different dimensionalityBielefeld, stabilized Postfach 10 01 31, D-33501 Bielefeld, Germany The anaerobic nitrite-reducing methanotroph ‘Candidatus Methylomirabilis oxyfera’ (‘Ca. M. oxyfera’) produces oxygen from nitrite by a lipid monolayer, to systematically probe the polymerization of bacterial cell-division protein FtsZ into fibrous networks as a function novel pathway. The major part of the concentrations O2 is used for methane activation and oxidation, which proceeds by the route well known for aerobic methanotrophs. Residual oxygen may serve other purposes, such as respiration. We have found that the genome of crowding agent‘Ca. M. oxyfera’ harbours four sets of genes encoding terminal respiratory oxidases: two cytochrome c oxidases, FtsZa third putative bo-type ubiquinol oxidase, and GTPa cyanide- insensitive alternative oxidase. FtsZ bundles confined Illumina sequencing of reverse-transcribed total community RNA and quantitative real-time RT-PCR showed that all four sets of genes were transcribed, albeit at low levels. Oxygen-uptake and inhibition experiments, UV–visible absorption spectral characteristics and EPR spectroscopy of solubilized membranes showed that only one of the four oxidases is functionally produced by ‘Ca. M. oxyfera’, notably the membrane-bound bo-type terminal oxidase. These findings open a new role for terminal respiratory oxidases in droplets were dynamicanaerobic systems, and their distribution depended on the intrinsic properties are an additional indication of the system and restrictions imposed by flexibility of terminal oxidases, of which the spatial boundariesdistribution among anaerobic micro-organisms may be largely underestimated.

End User Agreement. This publication is distributed under the terms of Article 25fa of the Dutch Copyright Act. This article entitles the maker of a short scientific work funded either wholly or partially by Dutch public funds to make that work publicly available for no consideration following a reasonable period of time after the work was first published, provided that clear reference is made to the source of the first publication of the work. Research outputs of researchers employed by Dutch Universities that comply with the legal requirements of Article 25fa of the Dutch Copyright Act, are distributed online and free of cost or other barriers in institutional repositories. Research outputs are distributed six months after their first online publication in the original published version and with proper attribution to the source of the original publication. You are permitted to download and use the publication for personal purposes. All rights remain with the author(s) and/or copyrights owner(s) of this work. Any use of the publication other than authorised under this licence or copyright law is prohibited. If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the University Library know, stating your reasons. In case of a legitimate complaint, the University Library will, as a precaution, make the material inaccessible and/or remove it from the website. Please contact the University Library through email: ▇▇▇▇▇▇▇▇▇@▇▇▇.▇▇.▇▇. You will be contacted as soon as possible. University Library Radboud University Published on 27 June 2013BLACK HOLE PHYSICS A dust-enshrouded tidal disruption event with a resolved radio jet in a galaxy merger S. Mattila1,2*†, ▇. ▇▇▇▇▇-Torres3,4*†, A. Efstathiou5, P. Mimica6, M. Fraser7,8, E. Kankare9, A. Alberdi3, M. Á. Aloy6, T. Heikkilä1, P. G. Jonker10,11, P. Lundqvist12, ▇. ▇▇▇▇▇-Vidal13, W. P. S. Meikle14, ▇. ▇▇▇▇▇▇-Cañizales15,16, S. J. Smartt9, S. Tsygankov1, ▇. Varenius13,17, ▇. ▇▇▇▇▇▇-Herrero18, M. Bondi19, C. Fransson12, ▇. ▇▇▇▇▇▇▇-Illana20, T. Kangas1,21, R. Kotak1,9, ▇. ▇▇▇▇▇▇▇-Olivencia3, P. Väisänen22,23, ▇. ▇. Beswick17, D. L. Clements14, R. Greimel24, ▇. Harmanen1, ▇. Kotilainen2,1, Downloaded by Radboud University Nijmegen on 9/5/2022 10:50:53 AM. Soft Matter PAPER Cite this: Soft Matter, 2013, 9, 10493 Received 26th April 2013 Accepted 27th June 2013 DOI: 10.1039/c3sm51163d from ▇▇▇▇▇://▇▇▇.▇▇▇.▇▇▇/▇▇▇▇▇▇▇.▇▇▇ Self-organization at Radboud University Nijmegen on May 03, 2024 K. Nandra25, T. Reynolds1, S. Ryder26, N. A. Walton8, ▇. Wiik1, G. Östlin12 Tidal disruption events (TDEs) are transient flares produced when a star is ripped apart by the gravitational field of a supermassive black hole (SMBH). We have observed a transient source in the western nucleus of the bacterial cellmerging galaxy pair Arp 299 that radiated >1.5 × 1052 erg at infrared and radio wavelengths but was not luminous at optical or x-division protein FtsZ in confined environments† ▇▇▇▇▇ ▇▇▇▇▇▇▇▇,‡a Begon~a ▇▇▇▇▇▇▇▇▇▇,‡b ▇▇▇▇▇▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇,a Esra ▇▇ ▇▇▇▇▇▇,a ▇▇▇▇▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇▇▇▇▇▇,a Germa´n ▇▇▇▇▇§*b and ▇▇▇▇▇▇▇ ▇ray wavelengths. ▇. ▇▇▇▇§*a We report a microfluidic approach to generate aqueous droplets in oil of different dimensionality, stabilized by a lipid monolayer, to systematically probe the polymerization of bacterial cell-division protein FtsZ into fibrous networks interpret this as a function TDE with much of its emission reradiated at infrared wavelengths by dust. Efficient reprocessing by dense gas and dust may explain the difference between theoretical predictions and observed luminosities of TDEs. The radio observations resolve an expanding and decelerating jet, probing the jet formation and evolution around a SMBH. T that the nuclear outburst had a peak brightness comparable to that of the concentrations of crowding agent, FtsZ, entire galaxy nucleus at both near-IR and GTPradio wavelengths (Fig. FtsZ bundles confined in droplets were dynamic, and their distribution depended 1) (7). Based on the intrinsic properties energetics and multiwavelength behavior of Arp 299-B AT1 over a decade of obser- vations (Figs. 1 to 3), two broad scenarios to ex- plain its origin are plausible: (i) an event unrelated to the system and restrictions imposed by SMBH, such as an extremely energetic SN, or a gamma-ray burst; or (ii) accretion-induced SMBH variability, such as an AGN flare, or a TDE. High–angular resolution [100 milli-arcsec (mas)], adaptive optics–assisted, near-IR imaging observations from the spatial boundaries.Gemini-North telescope

End User Agreement. This publication is distributed under the terms of Article 25fa of the Dutch Copyright Act. This article entitles the maker of a short scientific work funded either wholly or partially by Dutch public funds to make that work publicly available for no consideration following a reasonable period of time after the work was first published, provided that clear reference is made to the source of the first publication of the work. Research outputs of researchers employed by Dutch Universities that comply with the legal requirements of Article 25fa of the Dutch Copyright Act, are distributed online and free of cost or other barriers in institutional repositories. Research outputs are distributed six months after their first online publication in the original published version and with proper attribution to the source of the original publication. You are permitted to download and use the publication for personal purposes. All rights remain with the author(s) and/or copyrights owner(s) of this work. Any use of the publication other than authorised under this licence or copyright law is prohibited. If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the University Library know, stating your reasons. In case of a legitimate complaint, the University Library will, as a precaution, make the material inaccessible and/or remove it from the website. Please contact the University Library through email: ▇▇▇▇▇▇▇▇▇@▇▇▇.▇▇.▇▇. You will be contacted as soon as possible. University Library Radboud University Published Online‌ ▇▇▇ is a co-founder of International Physicians for Prevention of Nuclear War, the organisation awarded the 1985 Nobel Peace Prize. DGN is a co-founder of Physicians for Social Responsibility. We declare no competing interests. ▇▇▇▇▇▇▇ and Women’s Hospital (JEM), ▇▇▇▇-▇▇▇▇▇▇ Cancer Institute (DGN), and Boston Children’s Hospital (DGN), Harvard Medical School, Boston, MA 02115, USA 1 Ghinai I, ▇▇▇▇▇▇▇▇▇ ▇▇, ▇▇▇▇▇▇ ▇▇, et al. First known person-to-person transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the USA. Lancet 2020; 395: 1137–44. 2 ▇▇▇▇▇ ▇▇, ▇▇▇▇▇▇▇ ▇▇, ▇▇▇▇▇▇ S, et al. Human and ecologic effects in Massachusetts of an assumed thermonuclear attack on 27 June 2013the United States. Downloaded N Engl J Med 1962; 266: 1127–37. 3 ▇▇▇▇ ▇, ▇▇▇▇▇▇▇ E, ▇▇▇▇▇▇ J, ▇▇▇▇▇▇ H. The nuclear-arms race and the physician. N Engl J Med 1981; 304: 726–29. 4 ▇▇▇▇▇▇ ▇▇. Inadvertent nuclear war. Lancet 1988; 2: 559–60. 5 ▇▇▇▇▇ N, ▇▇▇▇▇, M, ▇▇▇▇▇▇ N, et al. The 2019 report of The Lancet Countdown on health and climate change: ensuring that the health of a child born today is not defined by Radboud University Nijmegen on 9/5/2022 10:50:53 AMa changing climate. Soft Matter PAPER Cite thisLancet 2019; 394: Soft Matter1836–78. 6 The New York Times Archives. The Einstein letter that started it all; a message to President ▇▇▇▇▇▇▇▇▇ 25 years ago launched the atom bomb and the atomic age. Aug 2, 2013, 9, 10493 Received 26th April 2013 Accepted 27th June 2013 DOI: 10.1039/c3sm51163d 1964. https:// ▇▇▇.▇▇▇▇▇▇▇.▇▇▇/▇▇▇▇/▇▇/▇▇▇▇ Self-organization of the bacterial cell-division protein FtsZ in confined environments† ▇▇▇▇▇ /▇▇▇▇▇▇▇▇,‡a Begon~a /▇▇▇- einstein-letter-that-started-it-all-a-message- to-president.html (accessed June 10, 2020). Governments worldwide have imple- mented school closures as a preventive measure to the spread of COVID-19. According to UNESCO, school closures have sent about 90% of all students out of school, among them more than 800 million girls. A substantial number of these girls live in the world’s least developed countries where getting an education is already a struggle. We agree with ▇▇▇▇▇▇▇,‡b ▇▇▇▇▇▇ and colleagues1 who recog- nise girls as a vulnerable group in the COVID-19 pandemic, stress two issues hindering girls’ education in developing countries, and challenge progress and commitment toward gender equality, girl empowerment, and the Sustainable Development Goals. The first issue relates to sexual and reproductive health aspects, where teenage girls might disproportionately drop out of school due to an increased risk of sexual exploitation, pregnancy, and (forced) marriage. School closures during the Ebola outbreak were asso- ciated with an increase in teenage pregnancies.2 Once schools re-opened, many “visibly pregnant girls”2 were banned from going back to school. With schools closing throughout the developing world, where stigma around teenage pregnancies prevails, we will probably see an increase in drop-out rates as teenage girls become pregnant or married. The second issue relates to socio- economic aspects, where girls might spend less time studying or might drop out of school at higher rates than boys because of a disproportionate increase in unpaid household work. Girls aged 5–14 years already spend 40% more time doing household work than boys do.3 As girls stay at home because of school closures, their household work burdens might increase, resulting in girls spending more time helping out at home instead of studying. This might encourage parents, particularly those putting a lower value on girls’ education, to keep their daughters at home even after schools reopen. Moreover, research shows that girls risk dropping out of school when caregivers are missing from the household because they typically have to (partly) replace the work done by the missing caregiver,4 who might be away due to COVID-19-related work, illness, or death. Therefore, with the current COVID-19 pandemic, we might see more girls than boys helping at home, lagging behind with studying, and dropping out of school. We warn that school closures in this COVID-19 pandemic may bolster gender gaps in education and girl empowerment dampening any pro- ▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇,already made, particularly in developing countries. We call for public acknowledgment and discussion about the adverse effects school closures can have on widening of the schooling gap between girls and boys. We call for a Esra ▇▇ ▇▇▇▇▇▇,a ▇▇▇▇gendered perspective in developing policy responses by tackling the sexual and reproductive health and socioeconomic issues addressed here to bring girls back to school after the measures to contain the COVID-19 pandemic end. We also ask governments to collect data specifically on non-paid housework and childcare responsibilities frequently ignored when investigating the consequences of child labour. Addressing the health and socioeconomic issues girls might face during this pandemic, as well as collecting data to quantify their effects, are important in honouring the commitment to the Sustainable Development Goals. We declare no competing interests. *▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇▇,a Germa´n ▇▇▇▇▇§*b and ▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇▇▇ ▇.▇▇▇▇▇▇▇▇▇@▇▇.▇▇.▇▇ Institute for Management Research, Radboud University, 6525 AJ Nijmegen, Netherlands (KB, GC); and ▇▇▇▇ ▇▇▇▇▇▇▇▇ Centre for Financial Studies, ▇▇▇▇ University, Lund, Sweden (KB) 1 Hall KS, Samari G, ▇▇▇▇▇▇▇ S, et al. Centring sexual and reproductive health and justice in the global COVID-19 response. Lancet 2020; 395: 1175–77. 2 ▇▇▇▇▇▇ JWT, ▇▇▇▇▇▇▇▇▇▇ C, ▇▇▇▇▇▇ P, ▇▇▇▇▇▇ J. The health impact of the 2015 Ebola outbreak. Public Health 2017; 143: 60–70. 3 UNICEF. Girls spend 160 million more hours than boys doing household chores everyday. Oct 7, 2016. ▇▇▇▇§*a We report a microfluidic approach to generate aqueous droplets in oil of different dimensionality▇://▇▇▇.▇▇▇▇▇▇.▇▇▇/press- releases/girls-spend-160-million-more-hours- boys-doing-household-chores-everyday (accessed April 10, stabilized by a lipid monolayer, to systematically probe the polymerization of bacterial cell-division protein FtsZ into fibrous networks as a function of the concentrations of crowding agent, FtsZ, and GTP. FtsZ bundles confined in droplets were dynamic, and their distribution depended on the intrinsic properties of the system and restrictions imposed by the spatial boundaries2020).

End User Agreement. This publication is distributed under the terms of Article 25fa of the Dutch Copyright Act. This article entitles the maker of a short scientific work funded either wholly or partially by Dutch public funds to make that work publicly available for no consideration following a reasonable period of time after the work was first published, provided that clear reference is made to the source of the first publication of the work. Research outputs of researchers employed by Dutch Universities that comply with the legal requirements of Article 25fa of the Dutch Copyright Act, are distributed online and free of cost or other barriers in institutional repositories. Research outputs are distributed six months after their first online publication in the original published version and with proper attribution to the source of the original publication. You are permitted to download and use the publication for personal purposes. All rights remain with the author(s) and/or copyrights owner(s) of this work. Any use of the publication other than authorised under this licence or copyright law is prohibited. If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the University Library know, stating your reasons. In case of a legitimate complaint, the University Library will, as a precaution, make the material inaccessible and/or remove it from the website. Please contact the University Library through email: ▇▇▇▇▇▇▇▇▇@▇▇▇.▇▇.▇▇. You will be contacted as soon as possible. University Library Radboud University Published on 27 June 2013Financiering, zekerheden en insolventie 214 Gemeenschappelijk Hof van Justitie van Aruba, Curaçao, Sint Maarten en van Bonaire, Sint Eustatius en Saba 13 oktober 2020, registratienrs. Downloaded by Radboud University Nijmegen on 9/5/2022 10:50:53 AMCUR202000211–CUR2020H00072, ECLI:NL:OGHACMB:2020:243 (mr. Soft Matter PAPER Cite this: Soft Matter, 2013, 9, 10493 Received 26th April 2013 Accepted 27th June 2013 DOI: 10.1039/c3sm51163d ▇▇▇.▇▇▇.▇▇▇/▇▇▇▇▇▇▇▇▇▇ Self-organization of the bacterial cell-division protein FtsZ in confined environments† ▇▇▇▇▇ ▇▇▇▇▇▇▇▇,‡a Begon~a ▇▇▇▇▇▇▇▇▇▇,‡b ▇▇▇▇▇▇▇▇▇▇ ▇▇▇ ▇▇▇▇, mr. Meijer, mr. Nijhuis) Noot ▇▇. ▇.▇,a Esra ▇▇ ▇▇▇▇▇▇,a ▇▇▇▇▇▇▇. ▇▇▇▇▇▇ Noot[▇▇.▇.▇▇▇▇▇▇▇▇▇,a Germa´n ▇▇▇▇▇§*b and ▇.▇▇▇▇▇▇ BW art. 3:94, 6:159, 6:162] gemachtigde: mr. J.A.M. Burgers, tegen de stichting Stichting SONA te Curaçao, geïntimeerde, gemachtigden: ▇▇. ▇. Frielink en ▇▇. ▇.▇. ▇▇▇▇§*a We report a microfluidic approach to generate aqueous droplets in oil of different dimensionality, stabilized by a lipid monolayer, to systematically probe the polymerization of bacterial cell-division protein FtsZ into fibrous networks as a function of the concentrations of crowding agent, FtsZ, and GTP▇. FtsZ bundles confined in droplets were dynamic, and their distribution depended on the intrinsic properties of the system and restrictions imposed by the spatial boundaries(...; red.)

End User Agreement. This publication is distributed under the terms of Article 25fa of the Dutch Copyright Act. This article entitles the maker of a short scientific work funded either wholly or partially by Dutch public funds to make that work publicly available for no consideration following a reasonable period of time after the work was first published, provided that clear reference is made to the source of the first publication of the work. Research outputs of researchers employed by Dutch Universities that comply with the legal requirements of Article 25fa of the Dutch Copyright Act, are distributed online and free of cost or other barriers in institutional repositories. Research outputs are distributed six months after their first online publication in the original published version and with proper attribution to the source of the original publication. You are permitted to download and use the publication for personal purposes. All rights remain with the author(s) and/or copyrights owner(s) of this work. Any use of the publication other than authorised under this licence or copyright law is prohibited. If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the University Library know, stating your reasons. In case of a legitimate complaint, the University Library will, as a precaution, make the material inaccessible and/or remove it from the website. Please contact the University Library through email: ▇▇▇▇▇▇▇▇▇@▇▇▇.▇▇.▇▇. You will be contacted as soon as possible. University Library Radboud University Published on 27 June 2013. Downloaded by Radboud University Nijmegen on 9/5/2022 10:50:53 AM. Soft Matter PAPER Cite this: Soft MatterJournal of Occupational and Organizational Psychology (2011), 201384, 9, 10493 Received 26th April 2013 Accepted 27th June 2013 DOI: 10.1039/c3sm51163d 215–227 ⃝C 2011 The British Psychological Society The British Psychological Society ▇▇▇.▇▇▇.▇▇▇/▇▇▇▇▇▇▇▇▇▇ Self-organization of the bacterial cell-division protein FtsZ in confined environments† ▇▇▇▇▇ ▇▇▇▇▇▇▇▇,‡a Begon~a ▇▇▇▇▇▇▇▇▇▇,‡b ▇▇▇▇▇▇▇▇▇▇ .▇▇▇ ▇▇▇▇▇▇▇▇,a Esra ▇▇ ▇▇▇▇▇▇,a ´ Schalk1,4∗, ▇▇▇▇▇▇▇▇ van der Heijden2,3, Annet de Lange2 and Marc van Veldhoven1 1Tilburg University, The Netherlands 2Radboud University Nijmegen, The Netherlands 3Institute for Management Research, Open Universiteit Nederland, The Netherlands ▇▇▇▇▇▇ ▇▇▇▇ ▇▇▇▇▇▇▇▇▇▇▇▇,a Germa´n , ▇▇▇▇▇§*b ▇▇▇▇▇▇▇▇, ▇▇▇▇▇ ▇▇▇▇▇▇ In the current era, characterized by dynamic societal, technological, and economic changes as well as an increasing diversity in the workforce, previous approaches to individual work behaviour are being challenged (▇▇▇▇▇▇ et al. 2010). Demographic trends in the working population, for example, ageing and de-juvenization (▇▇▇▇▇▇ & ▇▇▇▇▇ 2007), are prompting work and organizational psychologists to seek better insight into how individuals can cope with the rapid transformations in their technological, social, and economic environments. Longitudinal studies have provided evidence for the dynamic relations between work and work behaviour and point to the diversity of intra- individual change trajectories across time (see, e.g., ▇▇ ▇▇▇▇▇ & ▇▇▇▇▇▇▇ 2006; ▇▇▇▇▇▇ & ▇▇▇▇▇ 2004). To interpret the complex results of these dynamic relations, however, new and innovative theoretical as well as methodological perspectives on development are needed, with long-term developmental changes in work behaviour in particular deserving more attention. Most studies so far used a ‘between person’ approach, focusing on static differences, whereas the dynamic ‘within-person’ processes have been mostly neglected. This special section contains six papers that report innovative and important studies introducing new theoretical perspectives and methodological innovations in examining intra-individual developmental data. This editorial introduces the topic, discusses the contributions of the papers, and ends with conclusions and suggestions for future research. We first examine theoretical perspectives, which are addressed in three of the special section papers. Next, we focus on the methodological issues, elaborated in the remaining three papers. ∗Correspondence should be addressed to ▇▇▇▇´ ▇▇▇▇▇▇, ▇▇ Studies, Tilburg University, PO Box 90153, 5000 LE Tilburg, The DOI:10.1111/j.2044-8325.2011.02031.x A long-term developmental perspective on an individual’s work and career reveals multi- dimensional processes over time, constituted by the many changes that occur in the psychological, organizational as well as social and even societal functioning of employees (cf. ▇▇ ▇▇▇▇▇ et al. 2006). Taking a long-term approach acknowledges that people at every point in time have past experiences that they carry with them and that these experiences influence their choices, behaviour, self-concept or social identity, roles, and outcomes at work. Such series of experiences not only form a steady stream but are also influenced by critical events at work and in private life. With respect to the intra-individual psychological processes involved in an individual’s work and career, age-related changes have been documented in several fundamental constructs, such as identity, self-determination, work values, future time perspective, job (attribute) preferences, and work motivation. Although general life-span theories exist that address psychological changes over time [e.g., Super’s Life-span, Life-space conceptual framework (1957; 1963), ▇▇▇▇▇▇▇▇▇’▇ Developmental-Contextual model (▇▇▇▇▇▇▇▇▇, ▇▇▇▇▇▇, & ▇▇▇▇▇▇▇▇▇▇▇ 1986), and ▇▇▇▇▇▇▇▇▇▇’▇ Life-span Socio-emotional Selectivity theory (1998)], there is currently a lack of innovative studies based on theories that examine and explain intra-individual developmental changes in work behaviour, its antecedents, and its consequences across longer periods of time. First, there is a lack of research into age-related changes in processes such as future time perspective, motivation, and identity, with which to explain intra-individual changes in work behaviour across time. It is highly relevant to examine, for example, how motives, personal preferences, attitudes, and wisdom change and develop over time, and what impact these changes have on work behaviour, in connection with the potential decreases in performance capacity and employability as established in the work-related aging literature (▇▇▇▇▇ & ▇▇▇▇▇▇ 2003; ▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇▇▇, & ▇▇▇▇▇▇▇▇▇▇▇▇ 1999). An important question is whether changes in psychological processes over time can compensate for dwindling capacity in terms of, for instance, physical strength and memory. Second, there is a need to increase our understanding of intra-individual changes in employee–employer interactions over time (e.g., psychological contract relationships) in relation to work behaviour, enduring work ability, and related outcomes. In studying work-related topics, work and organizational psychology can borrow from the consolidated position and progress that has been made in the field of life course research in recent years (Billari 2009). The annual book series ‘Advances in Life Course Research’ has developed into a full-fledged, quarterly, scientific journal (Billari 2009), and the journal ‘Longitudinal and Life Course Studies’ has similarly become established (▇▇▇▇▇▇, ▇▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇▇, ▇▇▇▇▇▇▇, & ▇▇▇▇▇▇▇▇▇ 2009). The consolidation of life course research can be linked to four major advancements (Billari 2009). First, longitudinal research is booming, and large-scale developments in data gathering and analysis techniques have allowed scholars to use groundbreaking research approaches in order to study the life course connecting individual trajectories over time and the trajectories of linked individuals. Second, the increasingly international perspective has influenced the scope of life course research, including more attention for its context- specificity. Third, notwithstanding the promise of laboratory and societal experiments, it is natural experiments, using interdisciplinary approaches aimed at uncovering causal mechanisms, which are expected to be of high added value (Levy & the Pavie Team 2005). Fourth, while aging has always been at the heart of life course research, over the past two decades research into the dynamic inter-relationships between health and the life course has become crucial. Over the past three decades, lifespan psychology has evolved into a distinct con- ceptual area within developmental psychology (e.g., ▇▇▇▇▇▇ 1987; ▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇▇▇▇▇, & ▇▇▇▇▇▇▇▇▇▇ 2006; ▇▇▇▇▇▇▇▇▇▇▇▇, ▇▇, Lo¨vde´n, & ▇▇▇▇▇▇▇▇▇ 2007). According to the ‘Center for Lifespan Psychology’ at the ▇▇▇ ▇▇▇▇▇▇ Institute for Human Development, there are three guiding propositions for research within this domain. First, lifespan changes in individual behaviour are seen as the result of interactions between maturation, learning, and senescence. Therefore, ’the general goal . . . is to identify mechanisms that generate invariance and variability, constancy and change in behavioural repertoires ...’ (▇▇▇▇▇▇▇▇▇▇▇▇ et al. 2007, p. 231). Maturation and senescence refer to age-graded brain mechanisms and their effects on behaviour throughout life, while learning refers to changes in brain states induced by behaviour–environment interactions. It is important to note that maturation cannot take place without learning and vice versa. Similarly, the ways in which senescence influences brain functioning with ageing depends on an individual’s past and present learning and maturational history. Second, lifespan theory and methodology need to integrate evidence across domains of functioning, time scales, and levels of analysis. In other words, in order to attain a comprehensive picture of individual development, theory and practice need to be integrated across functional domains. More specifically, a better understanding of the mechanisms that link short-term variations to long-term change is needed (Li, ▇▇▇▇▇▇▇, & ▇▇▇▇▇▇▇▇▇ 2004; ▇▇▇▇▇▇▇▇▇▇▇▇ & ▇▇▇ ▇▇▇▇▇▇▇ 2006) as well as a better understanding of the connections between behavioural and neuronal levels of analysis. at work over time. Next, we introduce the three papers in the special section that address theoretical issues related to lifespan theories as discussed above. The study by ▇▇▇▇▇ and ▇▇▇ ▇▇ ▇▇▇▇▇▇ (2011, pp. 228–247) is a case in point, when it comes to testing long-term developmental theories in relation to work behaviour. In their two-wave (1-year time lag), longitudinal study among 600 Dutch university employees, they formulated and tested hypotheses based on an integration of two lifespan theories, namely the Selection Optimization and Compensation Theory (▇▇▇▇▇▇ et al. 1999), and the Socio-Emotional Selectivity Theory (▇▇▇▇▇▇▇▇▇▇ 1995). Specifically, according to the Selection Optimization with Compensation (SOC) model by ▇▇▇▇▇▇ et al. (1999), successful developmental regulation can be characterized by maximizing gains and minimizing losses through Selecting outcomes, Optimizing resources to reach those (desirable) outcomes, and Compensating for the age-related loss of outcome-relevant means (▇▇▇▇▇▇ et al. 1999; ▇▇ ▇▇▇▇▇ et al. 2010). On the other hand, the Socio-Emotional Selectivity theory (▇▇▇▇▇▇▇▇▇▇ 2006) focuses on the motivational consequences of a changing ‘temporal horizon’, and hypothesizes that individuals will select goals in accordance with their perceptions of the future as being limited or open-ended (▇▇▇▇ & ▇▇▇▇▇▇▇▇▇▇ 2002). More specifically, ▇▇▇▇▇ and ▇▇▇ ▇▇ ▇▇▇▇▇▇ (2011, pp. 228–247) examined whether changes in future time perspective could explain the relations between age-related health and generativity as well as developmental work motives as found in earlier research (cf. ▇▇▇▇§*a We report a microfluidic approach to generate aqueous droplets in oil of different dimensionality▇, stabilized ▇▇ ▇▇▇▇▇, ▇▇▇▇▇▇, ▇▇▇▇▇▇, & ▇▇▇▇▇▇▇ 2011). Their results revealed that negative relations between health and developmental motives can be explained by a lipid monolayerreduced focus on opportunities, whereas a temporal focus on limitations may explain the negative relation between health and generativity motives. Although the study has some methodological limitations, it is exemplary in that both theories used focus on individual attempts to cope with health losses across the lifespan and address fluctuations in both development and generativity motives. As such, the authors’ approach is a sound reflection of the viewpoints advocated by ▇▇▇▇▇▇▇▇▇▇ et al. (2010), and the paper responds to the call for more longitudinal age-comparative research aimed at a better understanding of long-term developmental trajectories (e.g., Lo¨vde´n et al. 2007; ▇▇▇▇▇▇ et al. 2003). Similarly, Schaufeli, ▇▇▇▇▇▇▇, ▇▇▇▇▇▇, and ▇▇▇▇▇ (2011, pp. 248–267), in a three-wave study examining stability and change in burnout among primary care physicians spanning a period of 10 years, used two lifespan approaches [i.e., the Selective Optimization and Compensation theory and the Motivational theory of Lifespan Development (Heckhausen et al. 2010)]. The authors were able to partial out the variance in burnout according to a stable and a dynamic component over time. The dynamic component is found to be the largest, representing three quarters of total variance, whereas the stable component amounts to one quarter. The paper confirms the expectation that burnout is a phenomenon that is, to systematically probe an important extent, stable over time for workers with a demanding job, for example, that of a physician. Patient demands are major determinants of burnout in physicians, although current demands appear to matter more than lagged- effects or long-term trends in (higher) patient demands across time. Both theoretically and conceptually, this paper contributes directly to the polymerization main goal in developmental psychology research, that is, to identify mechanisms that generate invariance and variability, constancy and change in behavioural repertoires (▇▇▇▇▇▇▇▇▇▇▇▇ et al. 2007, p. 231). Ten Brummelhuis, ▇▇▇ ▇▇▇▇▇▇, ▇▇▇▇▇▇, and ▇▇▇▇▇ (2011, pp. 268–287) also studied the phenomenon of bacterial cell-division protein FtsZ into fibrous networks burnout as a function process that develops over time. These authors used a different theoretical framework as a starting point, more specifically, the Conservation of Resources theory (Hobfoll 2002). ▇▇▇▇▇▇▇, according to this model, can be understood as the result of a long-term process of resource loss that is present in work behaviour in combination with accumulating job demands. The main contribution of this study lies in its examination of how motivation ties in with this process. The study is situated among employees working in a financial consultancy firm. It finds that burnout induces a loss cycle by depleting resources and increasing demand, but that job motivation can play an attenuating role in this regard. More specifically, intrinsic motivation helps employees break through the negative cycle of burnout. Extrinsic motivation, however, appears to aggravate the loss cycle. This study offers an excellent illustration of the concentrations dynamic interplay of crowding agentpersonal and situational factors over time in an individual worker’s career. The three papers of the special section discussed above contribute to theoretical advancement in the area of long-term developments in work behaviours. The other three papers make specific methodological contributions. Before we discuss these papers, FtsZwe will first introduce some general methodological issues involved in life-span developmental research. As stated by ▇▇▇▇▇▇▇ and ▇▇▇▇▇▇▇▇▇▇▇ (2003), the requirement that one has appropriate concepts and methods for evaluating how and why individuals change (or remain stable) as they grow older (▇▇▇▇▇▇ et al. 1999; Nesselroade 1991) lies at the heart of the science of aging. Fortunately, over the past four decades, considerable progress has been made in our understanding of how to operationalize the concept of ‘psychological change’ (see for instance, ▇▇▇▇▇▇ & ▇▇▇▇▇▇▇▇▇▇▇ 1979; ▇▇▇▇▇▇▇ & ▇▇▇▇▇ 2001; Little, ▇▇▇▇▇▇▇▇, & ▇▇▇▇▇▇▇ 2000). Again, the field of occupational and organizational psychology has much to learn from developmental psychology in dealing with such issues when studying long-term development at work. Scholars are required to carefully integrate and apply state-of-the-art knowledge across the domains of measurement, research design, and GTPstatistical modelling techniques (Nesselroade & ▇▇▇▇▇▇▇▇▇ 2003). FtsZ bundles confined As regards the first issue, ▇▇▇▇▇▇▇▇ (1963) has summarized and discussed several problems and dilemmas in droplets were dynamicthe measurement of change (such as, e.g., the correction for unreliability in the measurements being studied for evidence of change; see also ▇▇▇▇▇▇▇ 1966 for more specific information). As regards the research design, it is important to note that the choice of empirical variables, and their distribution depended on how well they represent the intrinsic properties of the system and restrictions imposed by the spatial boundaries.late

End User Agreement. This publication is distributed under the terms of Article 25fa of the Dutch Copyright Act. This article entitles the maker of a short scientific work funded either wholly or partially by Dutch public funds to make that work publicly available for no consideration following a reasonable period of time after the work was first published, provided that clear reference is made to the source of the first publication of the work. Research outputs of researchers employed by Dutch Universities that comply with the legal requirements of Article 25fa of the Dutch Copyright Act, are distributed online and free of cost or other barriers in institutional repositories. Research outputs are distributed six months after their first online publication in the original published version and with proper attribution to the source of the original publication. You are permitted to download and use the publication for personal purposes. All rights remain with the author(s) and/or copyrights owner(s) of this work. Any use of the publication other than authorised under this licence or copyright law is prohibited. If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the University Library know, stating your reasons. In case of a legitimate complaint, the University Library will, as a precaution, make the material inaccessible and/or remove it from the website. Please contact the University Library through email: ▇▇▇▇▇▇▇▇▇@▇▇▇.▇▇.▇▇. You will be contacted as soon as possible. University Library Radboud University Published on 27 June 06 February 2013. Downloaded by Radboud University Nijmegen on 9/5/2022 10:50:53 4/8/2019 9:10:16 AM. Soft Matter PCCP PAPER Cite this: Soft MatterPhys. Chem. Chem. Phys., 2013, 9Received 24th June 2012, 10493 Received 26th April 2013 Accepted 27th June 6th February 2013 DOI: 10.1039/c3sm51163d c3cp00158j ▇▇▇.▇▇▇.▇▇▇/▇▇▇▇ Infrared multiple photon dissociation (IRMPD) spectroscopy of oxazine dyes ▇▇▇▇▇▇ ▇. ▇▇▇▇▇▇▇▇,a ▇▇▇ Self-organization of the bacterial cell-division protein FtsZ in confined environments† ▇▇▇▇▇▇,*bcd ▇▇▇▇ ▇▇▇▇▇▇▇▇,‡a Begon~a ▇▇▇▇▇▇▇▇▇▇,‡b ▇▇▇▇▇▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇,a Esra ▇▇ ▇▇▇▇▇▇,a ▇▇▇▇▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇▇▇▇▇▇,a Germa´n ▇▇▇▇▇§*b ▇ and ▇▇▇▇▇▇▇ ▇. ▇. ▇▇▇▇§▇*a We report The structure and energetic properties of four common oxazine dyes, Nile red, Nile blue A, Cresyl violet, and Brilliant cresyl blue, have been probed using a microfluidic approach to generate aqueous droplets in oil combination of different dimensionality, stabilized by a lipid monolayer, to systematically probe the polymerization of bacterial cellinfrared multiple-division protein FtsZ into fibrous networks as a function photon dissociation (IRMPD) spectroscopy and quantum chemical calculations. IRMPD spectra of the concentrations protonated dyes, as generated from an electrospray ionization (ESI) source, were collected in the range of crowding agent, FtsZ, 900–1800 cm—1. Vibrational band assignments related to carbonyl and GTP. FtsZ bundles confined in droplets substituted-amine stretches were dynamic, and their distribution depended on the intrinsic properties established from a comparison of the system experimental spectra of these related systems as well as from a comparison with spectra generated by density functional theory (DFT) calculations. For Nile red, the thermochemical landscape for protonation at different basic sites was probed using DFT; comparison of IRMPD and restrictions imposed by calculated IR spectra reveals the spatial boundariessite of protonation to be at the carbonyl oxygen. The structural information obtained here in the gas phase pertaining to these important fluorophores is anticipated to provide further insight into their associated intrinsic fluorescent properties in solution.

End User Agreement. This publication is distributed under the terms of Article 25fa of the Dutch Copyright Act. This article entitles the maker of a short scientific work funded either wholly or partially by Dutch public funds to make that work publicly available for no consideration following a reasonable period of time after the work was first published, provided that clear reference is made to the source of the first publication of the work. Research outputs of researchers employed by Dutch Universities that comply with the legal requirements of Article 25fa of the Dutch Copyright Act, are distributed online and free of cost or other barriers in institutional repositories. Research outputs are distributed six months after their first online publication in the original published version and with proper attribution to the source of the original publication. You are permitted to download and use the publication for personal purposes. All rights remain with the author(s) and/or copyrights owner(s) of this work. Any use of the publication other than authorised under this licence or copyright law is prohibited. If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the University Library know, stating your reasons. In case of a legitimate complaint, the University Library will, as a precaution, make the material inaccessible and/or remove it from the website. Please contact the University Library through email: ▇▇▇▇▇▇▇▇▇@▇▇▇.▇▇.▇▇. You will be contacted as soon as possible. University Library Radboud University Published on 27 June 2013. Downloaded by Radboud University Nijmegen on 9/5/2022 10:50:53 AM. Soft Matter PAPER Cite this: Soft MatterLuke van Leijenhorst1,3(✉) , 2013Arjen P. de Vries1 , 9, 10493 Received 26th April 2013 Accepted 27th June 2013 DOI: 10.1039/c3sm51163d ▇▇▇.▇▇▇.▇▇▇/▇▇▇▇▇▇▇▇▇▇ Self-organization of the bacterial cell-division protein FtsZ in confined environments† ▇▇▇▇▇ ▇▇▇▇▇▇ Jansen2 , and ▇▇▇,‡a Begon~a ▇▇▇ Wertheim3 1 Institute for Computing and Information Sciences, Radboud University, Nijmegen, Netherlands {luke.vanleijenhorst,▇▇▇▇▇.▇▇▇▇▇▇▇}@▇▇▇,‡b ▇▇▇▇▇▇▇▇.▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇,2 Department of Infection Prevention and Control, Amphia Hospital, 3 Department of Medical Microbiology, Radboudumc, Nijmegen, Netherlands In healthcare, medical knowledge is captured into guidelines that support health- care professionals to deliver the best possible quality of care. In hospitals and other healthcare settings, these guidelines are implemented and integrated in local standard operating procedures (SOPs). When guidelines are updated, it is important to also update all SOPs that are based on this guideline. In most hospitals, this is a Esra ▇▇ ▇▇▇▇▇▇,a ▇▇▇▇▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇▇▇▇▇▇,a Germa´n ▇▇▇▇▇§*b and ▇▇▇▇▇▇▇ ▇. manual process in which employees periodically adjust the Oc The Author(s), under exclusive license to Springer Nature Switzerland AG 2023 ▇. ▇▇▇▇§*▇ et al. (Eds.): ECIR 2023, LNCS 13982, pp. 307–312, 2023. ▇▇▇▇▇://▇▇▇.▇▇▇/10.1007/978-3-031-28241-6_31 SOPs associated with the guideline in the quality system. Given the number of guidelines and the number of SOPs in a We report hospital, this is a microfluidic approach vulnerable process that may lead to generate aqueous droplets in oil of different dimensionality, stabilized by SOPs that are (partially) outdated. SOPalign is a lipid monolayer, tool that uses natural language processing techniques to systematically probe assess where SOPs are compliant with the polymerization of bacterial cell-division protein FtsZ into fibrous networks as a function of the concentrations of crowding agent, FtsZapplicable guidelines, and GTPwhere they dif- fer. FtsZ bundles confined The tool can support healthcare facilities to keep their procedures updated with the guidelines. It also helps to discover bottlenecks in droplets were dynamicthe guideline rec- ommendations, when recommendations in guidelines do not appear in SOPs, or the SOPs are not compliant with the guideline. This is an important step in the improvement cycle of guidelines and their distribution depended on supports the intrinsic properties perspective of the system ‘living guidelines’. The authors foresee a transition from a collection of independent documents into a hyperlinked network of guidelines and restrictions imposed by the spatial boundariesSOPs. Our tool aims to enable this transition at a low cost.

End User Agreement. This publication is distributed under the terms of Article 25fa of the Dutch Copyright Act. This article entitles the maker of a short scientific work funded either wholly or partially by Dutch public funds to make that work publicly available for no consideration following a reasonable period of time after the work was first published, provided that clear reference is made to the source of the first publication of the work. Research outputs of researchers employed by Dutch Universities that comply with the legal requirements of Article 25fa of the Dutch Copyright Act, are distributed online and free of cost or other barriers in institutional repositories. Research outputs are distributed six months after their first online publication in the original published version and with proper attribution to the source of the original publication. You are permitted to download and use the publication for personal purposes. All rights remain with the author(s) and/or copyrights owner(s) of this work. Any use of the publication other than authorised under this licence or copyright law is prohibited. If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the University Library know, stating your reasons. In case of a legitimate complaint, the University Library will, as a precaution, make the material inaccessible and/or remove it from the website. Please contact the University Library through email: ▇▇▇▇▇▇▇▇▇@▇▇▇.▇▇.▇▇. You will be contacted as soon as possible. University Library Radboud University Published on 27 June 2013. Downloaded by Radboud University Nijmegen on 9/5/2022 10:50:53 AM. Soft Matter PAPER Cite this: Soft MatterConsolidative Dendritic Cell-based Immunotherapy Elicits Cytotoxicity against Malignant Mesothelioma Joost P. Hegmans1, 2013Joris D. Veltman1, 9, 10493 Received 26th April 2013 Accepted 27th June 2013 DOI: 10.1039/c3sm51163d ▇▇▇.▇▇▇.▇▇▇/▇▇▇▇▇▇▇▇▇▇ Self-organization of the bacterial cell-division protein FtsZ in confined environments† ▇▇▇▇▇ ▇▇▇▇▇▇▇▇,‡a Begon~a ▇▇▇▇▇▇▇▇▇▇,‡b ▇▇▇▇▇▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇,a Esra ▇▇ ▇▇▇▇▇▇,a ▇▇▇▇▇▇. Lambers1, I. ▇▇▇▇▇▇▇ ▇. de Vries2, ▇▇▇▇ ▇. Figdor2, ▇▇▇▇ ▇. Hendriks1, Henk C. Hoogsteden1, ▇▇▇▇ ▇▇,a Germa´n ▇▇▇▇▇§*b . Lambrecht1,3, and ▇▇▇▇▇▇▇ ▇. ▇. ▇▇▇▇§*a We report a microfluidic approach to generate aqueous droplets in oil Aerts1,4 1Department of different dimensionalityPulmonary Medicine, stabilized by a lipid monolayerErasmus MC, to systematically probe the polymerization Rotterdam, The Netherlands; 2Department of bacterial cell-division protein FtsZ into fibrous networks as a function Tumor Immunology, Nijmegen Centre for Molecular Life Sciences (NCMLS), Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands; 3Department of the concentrations Respiratory Medicine, Ghent University, Ghent, Belgium; 4Department of crowding agentPulmonary Medicine, FtsZAmphia Hospital, and GTP. FtsZ bundles confined in droplets were dynamicBreda, and their distribution depended on the intrinsic properties of the system and restrictions imposed by the spatial boundaries.The Netherlands

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All rights remain with the author(s) and/or copyrights owner(s) of this work. Any use of the publication other than authorised under this licence or copyright law is prohibited. If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the University Library know, stating your reasons. In case of a legitimate complaint, the University Library will, as a precaution, make the material inaccessible and/or remove it from the website. Please contact the University Library through email: ▇▇▇▇▇▇▇▇▇@▇▇▇.▇▇.▇▇. You will be contacted as soon as possible. University Library Radboud University Published on 27 June 2013. Downloaded by Nicolas Bordes1(✉), ▇▇▇▇ Daemen2, Dani¨el Kuijsters2, and Gilles Van Assche3 1 Universit´e Grenoble Alpes, Grenoble, France 2 Radboud University Nijmegen on 9/5/2022 10:50:53 AM. Soft Matter PAPER Cite this: Soft MatterUniversity, 2013Nijmegen, 9, 10493 Received 26th April 2013 Accepted 27th June 2013 DOI: 10.1039/c3sm51163d The Netherlands {▇▇▇▇.▇▇▇▇▇▇,▇▇▇▇▇▇.▇▇▇▇▇▇▇▇▇}@▇▇.▇▇ 3 Modern block ciphers and cryptographic permutations consist of the iteration of a round function. In many cases this round function consists of a layer of nonlinear S-boxes, a mixing layer, a shuffle layer (AKA a bit transposition or bit permutation), and the addition of a round key (in block ciphers) or constant (in cryptographic permutations). Electronic supplementary material The online version of this chapter (https:// ▇▇▇.▇▇▇/▇▇.▇▇▇▇/▇▇▇-▇-▇▇▇-▇▇▇▇▇-▇ 12) contains supplementary material, which is available to authorized users. Oc International Association for Cryptologic Research 2021 ▇. ▇▇▇▇▇▇ and ▇. ▇▇▇▇▇▇▇ Self-organization of the bacterial cell-division protein FtsZ in confined environments† ▇▇▇▇▇ (Eds.): CRYPTO 2021, LNCS 12827, pp. 337–367, 2021. ▇▇▇▇▇://▇▇▇,‡a Begon~a .▇▇▇▇▇▇▇▇▇▇,‡b ▇▇▇▇▇▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇,/10.1007/978-3-030-84252-9_12 Many papers investigate S-boxes and try to find a Esra ▇▇ ▇▇▇▇▇▇,good compromise between implementation cost and propagation properties or provide a ▇▇▇▇▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇▇▇▇▇▇,classification of all invertible S-boxes of a Germa´n ▇▇▇▇▇§*b given width, see, e.g., [27, 34]. Similarly, there is a rich literature on certain types of mixing layers. In particular, there have been many papers written about finding maximum-distance separable (MDS) mappings or near-MDS mappings with minimum implementation cost according to some met- ric, see, e.g., [28, 37]. Building a good cipher starts with taking a good S-box and ▇▇▇▇▇▇▇ ▇mixing layer and the rich cryptographic literature on these components provides us with ample choice. ▇However, how these building blocks are combined in a round function and the resulting propagation properties has received much less systematic attention. ▇▇▇▇§*A standard way for designing a We report a microfluidic approach to generate aqueous droplets good round function from an S-box and an MDS mapping is the one followed in oil the Advanced Encryption Standard (AES) [32] and is known as the wide trail strategy [14, 20]. This strategy gives criteria for the shuffle layer and comes with easy-to-verify bounds for the differen- tial probability (DP) of different dimensionality, stabilized by a lipid monolayer, to systematically probe differential trails (also known as characteristics) and the polymerization linear potential (LP) of bacterial cell-division protein FtsZ into fibrous networks as a function linear trails. These bounds and its simplicity have made it one of the concentrations of crowding agent, FtsZmost applied design strategies, and GTPAES has inspired a plethora of primitive designs, including lightweight ones. FtsZ bundles confined By adopting 4-bit S-boxes instead of 8-bit ones and modern lightweight MDS layers in droplets a smart structure, multi- ple lightweight ciphers have been constructed. Many lessons were dynamiclearned and this line of design has culminated in the block cipher of the NIST lightweight competition candidate Saturnin [12], a truly modern version of AES. Naturally, there are alternative design approaches. A popular design approach is the one underlying the 64-bit lightweight block cipher Present [10]. Its round function has no MDS layer and simply consists of an S-box layer, a bit shuffle, and a key addition. It gets its diffusion from the combination of a smart choice of the bit shuffle and specific propagation criteria from its well-chosen S-box and doing many rounds. The Present line of design has also been refined in the form of the Gift (64- and 128-bit) block ciphers [1] and the cryptographic permutations of the Spongent lightweight hash function [9] that is used in Elephant [7]. Another distinctive design approach is that of the cryptographic permutation of the SHA-3 standard [33], Keccak-f . Unlike Present, its round function does have a mixing layer, and it actually has all ingredients that AES has. Specifically, in their distribution depended rationale, the designers also refer to the wide trail design strategy [6]. However, this wide-trail flavor does not appear to come with the simple bounds as in the case of AES, and designers have to resort to tedious and time-consuming programming efforts to obtain similar bounds. This is related to the fact that AES operates on bytes and Keccak-f on bits. The Keccak-f designers have discussed the difference between these two design approaches in [18]. In that paper, they have coined the term alignment to characterize this difference and supported it with some propagation experiments on Keccak-f . The Keccak-f line of design has also been refined and led to the 384-bit permutation that is used in Xoodyak [15], namely Xoodoo [16], a truly modern version of Keccak-f . This treatment is not exhaustive and other distinctive design strategies exist. alternating Additions with Rotations and XOR (ARX) such as Salsa [3], or they iterate very simple round functions many times such as Simon [2]. In this paper we systematically analyze the impact of alignment on the intrinsic differ- ential and linear propagation properties of ciphers. We show that certain design choices regarding how the system S-box and restrictions imposed by mixing layers are combined have a pro- found impact on the spatial boundariespropagation properties. We identify and name a number of effects that are relevant in this context. Furthermore, we believe that this makes it possible to give a meaningful and non-ambiguous definition of the term alignment.

End User Agreement. This publication is distributed under the terms of Article 25fa of the Dutch Copyright Act. This article entitles the maker of a short scientific work funded either wholly or partially by Dutch public funds to make that work publicly available for no consideration following a reasonable period of time after the work was first published, provided that clear reference is made to the source of the first publication of the work. Research outputs of researchers employed by Dutch Universities that comply with the legal requirements of Article 25fa of the Dutch Copyright Act, are distributed online and free of cost or other barriers in institutional repositories. Research outputs are distributed six months after their first online publication in the original published version and with proper attribution to the source of the original publication. You are permitted to download and use the publication for personal purposes. All rights remain with the author(s) and/or copyrights owner(s) of this work. Any use of the publication other than authorised under this licence or copyright law is prohibited. If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the University Library know, stating your reasons. In case of a legitimate complaint, the University Library will, as a precaution, make the material inaccessible and/or remove it from the website. Please contact the University Library through email: ▇▇▇▇▇▇▇▇▇@▇▇▇.▇▇.▇▇. You will be contacted as soon as possible. University Library Radboud University Published on 27 June 2013. Downloaded by Radboud University Nijmegen on 9/5/2022 10:50:53 AM. Soft Matter PAPER Cite this: Soft Matter, 2013, 9, 10493 Received 26th April 2013 Accepted 27th June 2013 DOI: 10.1039/c3sm51163d ▇▇▇.▇▇▇.▇▇▇/▇▇▇▇ Schwabe1,2, ▇▇▇▇▇▇▇ Self-organization of the bacterial cell-division protein FtsZ in confined environments† Stebila3, and Thom Wiggers2(✉) 1 ▇▇▇ ▇▇▇▇▇▇ Institute for Security and Privacy, Bochum, Germany 2 Radboud University, Nijmegen, The Netherlands 3 University of Waterloo, Waterloo, Canada Abstract. While server-only authentication with certificates is the most widely used mode of operation for the Transport Layer Security (TLS) protocol on the world wide web, there are many applications where TLS is used in a different way or with different constraints. For example, embedded Internet-of-Things clients may have a server certificate pre- programmed and be highly constrained in terms of communication band- width or computation power. As post-quantum algorithms have a wider range of performance trade-offs, designs other than traditional “signed- key-exchange” may be worthwhile. The KEMTLS protocol, presented at ACM CCS 2020, uses key encapsulation mechanisms (KEMs) rather than signatures for authentication in the TLS 1.3 handshake, a benefit since most post-quantum KEMs are more efficient than PQ signatures. How- ever, KEMTLS has some drawbacks, especially in the client authentica- tion scenario which requires a full additional roundtrip. We explore how the situation changes with pre-distributed public keys, which may be viable in many scenarios, for example pre-installed pub- lic keys in apps, on embedded devices, cached public keys, or keys dis- tributed out of band. Our variant of KEMTLS with pre-distributed keys, called KEMTLS-PDK, is more efficient in terms of both bandwidth and computation compared to post-quantum signed-KEM TLS (even cached public keys), and has a smaller trusted code base. When client authenti- cation is used, KEMTLS-PDK is more bandwidth efficient than KEMTLS yet can complete client authentication in one fewer round trips, and has stronger authentication properties. Interestingly, using pre-distributed keys in KEMTLS-PDK changes the landscape on suitability of PQ algo- rithms: schemes where public keys are larger than ciphertexts/signatures (such as Classic McEliece and Rainbow) can be viable, and the differ- ences between some lattice-based schemes is reduced. We also discuss how using pre-distributed public keys provides privacy benefits compared to pre-shared symmetric keys in TLS. Keywords: Post-quantum cryptography · Transport Layer Security ▇▇ ▇▇▇▇▇▇▇▇ Nature Switzerland AG 2021 ▇,‡a Begon~a . ▇▇▇▇▇▇▇ et al. (Eds.): ESORICS 2021, LNCS 12972, pp. 3–22, 2021. ▇▇▇▇▇://▇▇▇.▇▇▇/10.1007/978-3-030-88418-5_1 The Transport Layer Protocol (TLS) is among the most-used secure channel pro- tocols. In August 2018, the most recent version was standardized as TLS 1.3 [38]. TLS 1.3 uses an (elliptic curve) Diffie–▇▇▇▇▇▇▇ key exchange to establish an ephemeral shared secret with forward secrecy. Server (and optionally client) authentication is provided by digital signatures. Long-term signature public keys are exchanged in certificates during the handshake. The most commonly used signature algorithm is RSA, although elliptic curve signatures are also supported. Migrating to Post-quantum TLS. To protect against quantum adversaries, effort has been made to move the TLS handshake towards post-quantum cryp- tography. The focus has largely been on upgrading the key exchange to post- quantum security. In [8], ▇▇▇, ▇▇▇▇▇▇▇▇▇▇,‡b ▇▇▇, ▇▇▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇,a Esra ▇▇ ▇▇▇▇▇▇,a ▇▇▇▇▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇▇▇▇▇▇,a Germa´n ▇▇▇▇▇§*b and ▇▇▇▇▇▇▇ ▇. ▇. showed how to replace Diffie–▇▇▇▇§*▇▇▇ by lattice-based key agreement in TLS 1.3. The lattice- based scheme was improved in the NewHope proposal [2], which was used in the first real-world post-quantum TLS experiment by Google in 2016 [9]. A second, more wide-scale, post-quantum TLS experiment by Google and Cloudflare has been running since 2019 [29, 31]. Post-quantum authentication in TLS is widely believed to be less urgent, as attacks against authentication cannot be mounted retroactively. However, several works also investigated the use of post-quantum signature schemes and certificates in TLS [5, 6, 44] by dropping in replacements of post-quantum primitives into the existing TLS 1.3 handshake and PKI infras- tructure. KEMTLS [43] is a recent proposal that makes more radical changes to the TLS 1.3 handshake. Instead of Diffie–▇▇▇▇▇▇▇ and signatures, KEMTLS uses key-encapsulation mechanisms (KEMs) not just for confidentiality, but also for authentication. The main motivation for this design is that most post-quantum KEMs are much more efficient, both computationally and in terms of bandwidth requirements, than post-quantum signature schemes. Additional advantages are a smaller trusted code base and offline deniability. We report give a microfluidic approach high-level overview of KEMTLS in comparison to generate aqueous droplets the TLS 1.3 handshake in oil Appendix A. 1.1 Pre-distributed Keys Fig. 1. Overview of different dimensionalityKEMTLS-PDK variants Contributions of This Paper. In this paper we investigate how this situa- tion changes with the move to post-quantum cryptography, stabilized by both when caching signature-based certificates in the TLS 1.3 handshake, but more importantly when using KEM-based authentication as used in KEMTLS. More specifically, – we introduce KEMTLS-PDK, a lipid monolayer, to systematically probe variant of KEMTLS that makes use of pre- distributed keys for earlier authentication in the polymerization protocol flow; – we describe KEMTLS-PDK with proactive client authentication and show that the benefits of bacterial cellearlier authentication are even more significant; – we analyse the security properties of KEMTLS-division protein FtsZ into fibrous networks as PDK (a function complete proof in the standard model is in the full version of the concentrations paper, available online); – we implement KEMTLS-PDK in the Rustls library using different instantia- tions of crowding agent, FtsZthe KEMs with NIST PQC round-3 candidates; and – we evaluate the performance of KEMTLS-PDK in comparison to TLS 1.3 instantiated with different post-quantum primitives and pre-distributed (cached) server certificates, and GTPin comparison to KEMTLS. FtsZ bundles confined We give a sketch of KEMTLS-PDK in droplets were dynamicFig. 1a. The central property to observe is that, like in TLS 1.3, but unlike in KEMTLS, the first message from the server Table 1. Summary of performance characteristics of KEMTLS, signed-KEM TLS 1.3 with cached server certificate, and their distribution depended KEMTLS-PDK KEMTLS Cached TLS KEMTLS-PDK Round trips until client receives response data Size (bytes) of public key crypto objects transmitted: 3 3 3 • Minimum PQ 932 499 561 • Module-LWE/Module-SIS (Kyber, Dilithium) 5,556 3,988 2,336 • NTRU-based (NTRU, Falcon) Mutually authentic 3,486ated 2,088 2,144 Round trips until client receives response data 4 3 3 Size (bytes) of public key crypto objects transmitted: • Minimum PQ 1,431 2,152 1,060 • MLWE/MSIS 9,554 10,140 6,324 • NTRU 5,574 4,365 4,185 serves as key confirmation. This means that in this variant on KEMTLS, like in TLS 1.3, the intrinsic properties server is explicitly authenticated after a single round trip. Also like TLS 1.3, the server can send data to the client first. The version of KEMTLS-PDK with proactive client authentication is shown in Fig. 1b. We give a brief summary how this affects performance in Table 1, for a vari- ety of post-quantum algorithm combinations. We see that client authentication in KEMTLS-PDK is just as efficient in terms of round trips as in TLS 1.3. How- ever, in terms of bandwidth requirements, KEMTLS-PDK is more efficient than TLS 1.3 with cached certificates (Cached TLS) for most instantiations. We will discuss this in more detail in Sect. 5, but the system unilaterally authenticated “Min- imum PQ” instantiation actually shows another interesting effect of consider- ing TLS with cached keys: KEMs and restrictions imposed by signature schemes with small cipher- texts/signatures, such as Classic McEliece [1] or Rainbow [16], not only become viable but are the spatial boundariesmost efficient instantiation.

End User Agreement. This publication is distributed under the terms of Article 25fa of the Dutch Copyright Act. This article entitles the maker of a short scientific work funded either wholly or partially by Dutch public funds to make that work publicly available for no consideration following a reasonable period of time after the work was first published, provided that clear reference is made to the source of the first publication of the work. Research outputs of researchers employed by Dutch Universities that comply with the legal requirements of Article 25fa of the Dutch Copyright Act, are distributed online and free of cost or other barriers in institutional repositories. Research outputs are distributed six months after their first online publication in the original published version and with proper attribution to the source of the original publication. You are permitted to download and use the publication for personal purposes. All rights remain with the author(s) and/or copyrights owner(s) of this work. Any use of the publication other than authorised under this licence or copyright law is prohibited. If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the University Library know, stating your reasons. In case of a legitimate complaint, the University Library will, as a precaution, make the material inaccessible and/or remove it from the website. Please contact the University Library through email: ▇▇▇▇▇▇▇▇▇@▇▇▇.▇▇.▇▇. You will be contacted as soon as possible. University Library Radboud University Published on 27 June 2013▇. Downloaded by Radboud University Nijmegen on 9/5/2022 10:50:53 AM▇. Soft Matter PAPER Cite this▇▇▇ ▇▇▇▇ et al.: Soft MatterCoherent Plasmon–Phonon Oscillations in a GaAs Sample 9l phys. stat. sol. (b) 204, 2013, 9, 10493 Received 26th April 2013 Accepted 27th June 2013 DOI9l (l997) Subject classification: 10.1039/c3sm51163d ▇▇▇.▇▇▇.▇▇; 72.30.+q; 73.30.+y; S7.l2 Coherent Plasmon–Phonon Oscillations in a GaAs Schottky Barrier Sample ▇/. ▇. ▇▇▇▇▇▇▇ ▇▇▇▇ Self-organization of the bacterial cell-division protein FtsZ in confined environments† (a), ▇. ▇▇ ▇▇▇▇ (b), ▇. ▇▇▇ ▇▇▇▇▇▇▇▇,‡a Begon~a ▇▇▇▇▇▇▇▇▇▇,‡b ▇▇▇▇▇▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇,a Esra ▇▇ ▇▇▇▇▇▇,a ▇▇▇▇▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇▇▇▇▇▇,a Germa´n ▇▇▇▇▇§*b and ▇▇▇▇▇▇▇ ▇. ▇. ▇▇▇▇§*a We report a microfluidic approach to generate aqueous droplets in oil of different dimensionality, stabilized by a lipid monolayer, to systematically probe the polymerization of bacterial cell-division protein FtsZ into fibrous networks as a function of the concentrations of crowding agent, FtsZ(b), and GTPTh. FtsZ bundles confined in droplets were dynamicRASiNG (b) (a) Physics Department, and their distribution depended on the intrinsic properties Eindhoven University of the system and restrictions imposed by the spatial boundaries.Technology, PO Box 513, NL−5600 MB Eindhoven, The Netherlands l) (b) Research Institute for Materials, Toernooiveld, NL−6525 ED Nijmegen, The Netherlands

End User Agreement. This publication is distributed under the terms of Article 25fa of the Dutch Copyright Act. This article entitles the maker of a short scientific work funded either wholly or partially by Dutch public funds to make that work publicly available for no consideration following a reasonable period of time after the work was first published, provided that clear reference is made to the source of the first publication of the work. Research outputs of researchers employed by Dutch Universities that comply with the legal requirements of Article 25fa of the Dutch Copyright Act, are distributed online and free of cost or other barriers in institutional repositories. Research outputs are distributed six months after their first online publication in the original published version and with proper attribution to the source of the original publication. You are permitted to download and use the publication for personal purposes. All rights remain with the author(s) and/or copyrights owner(s) of this work. Any use of the publication other than authorised under this licence or copyright law is prohibited. If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the University Library know, stating your reasons. In case of a legitimate complaint, the University Library will, as a precaution, make the material inaccessible and/or remove it from the website. Please contact the University Library through email: ▇▇▇▇▇▇▇▇▇@▇▇▇.▇▇.▇▇. You will be contacted as soon as possible. University Library Radboud University Published on 27 June 2013. Downloaded by Radboud University Nijmegen on 9/5/2022 10:50:53 AM. Soft Matter PAPER Cite this: Soft Matter, 2013, 9, 10493 Received 26th April 2013 Accepted 27th June 2013 DOI: 10.1039/c3sm51163d ▇▇▇.▇▇▇.▇▇▇/▇▇▇▇▇▇▇▇▇▇ SelfBeyne1, Yu Long Chen1, Christoph Dobraunig2, and Bart Mennink3(✉) 1 KU Leuven and imec-organization COSIC, Leuven, Belgium 2 Lamarr Security Research, Graz, Austria 3 Radboud University, Nijmegen, The Netherlands Abstract. One of the bacterial cellfinalists in the NIST Lightweight Cryptography competition is Elephant v2, a parallelizable, permutation-division protein FtsZ based authen- ticated encryption scheme. The original first/second-round submission Elephant v1/v1.1 was proven secure against nonce-respecting adversaries in confined environments† ▇▇▇▇▇ ▇▇▇▇▇▇▇▇,‡a Begon~the single-user setting. For the final round, the mode has undergone certain subtle modifications, the most important one being a ▇▇▇▇▇▇▇▇▇▇,‡b ▇▇▇▇▇▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇,a Esra ▇▇ ▇▇▇▇▇▇,a ▇▇▇▇▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇▇▇▇▇▇,a Germa´n ▇▇▇▇▇§*b and ▇▇▇▇▇▇▇ ▇. ▇. ▇▇▇▇§*a We report a microfluidic approach to generate aqueous droplets change in oil of different dimensionality, stabilized by a lipid monolayer, to systematically probe the polymerization of bacterial cell-division protein FtsZ into fibrous networks as a function authentication portion of the concentrations of crowding agentmode. These changes require a new dedicated security proof. 1. In addition, FtsZour security analysis is in the multi-user setting and demonstrates that Elephant v2 fares well if multiple devices use Elephant v2 with independent keys. Moreover, and GTPour proof shows that Elephant v2 even ensures authenticity under nonce misuse. FtsZ bundles confined in droplets were dynamic, and their distribution depended on the intrinsic properties of the system and restrictions imposed by the spatial boundaries.Keywords: Authenticated encryption · Lightweight · Elephant · Multi-user security · Nonce-misuse

End User Agreement. This publication is distributed under the terms of Article 25fa of the Dutch Copyright Act. This article entitles the maker of a short scientific work funded either wholly or partially by Dutch public funds to make that work publicly available for no consideration following a reasonable period of time after the work was first published, provided that clear reference is made to the source of the first publication of the work. Research outputs of researchers employed by Dutch Universities that comply with the legal requirements of Article 25fa of the Dutch Copyright Act, are distributed online and free of cost or other barriers in institutional repositories. Research outputs are distributed six months after their first online publication in the original published version and with proper attribution to the source of the original publication. You are permitted to download and use the publication for personal purposes. All rights remain with the author(s) and/or copyrights owner(s) of this work. Any use of the publication other than authorised under this licence or copyright law is prohibited. If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the University Library know, stating your reasons. In case of a legitimate complaint, the University Library will, as a precaution, make the material inaccessible and/or remove it from the website. Please contact the University Library through email: ▇▇▇▇▇▇▇▇▇@▇▇▇.▇▇.▇▇. You will be contacted as soon as possible. University Library Radboud University Published Impacts of biogenic CO2 emissions on 27 June 2013. Downloaded by Radboud University Nijmegen human health and terrestrial ecosystems: the case of increased wood extraction for bioenergy production on 9/5/2022 10:50:53 AM. Soft Matter PAPER Cite this: Soft Matter, 2013, 9, 10493 Received 26th April 2013 Accepted 27th June 2013 DOI: 10.1039/c3sm51163d a global scale ROS A LIE V AN ▇▇▇.▇ 1 , PATIENCE A . N . M UCHADA 1 , M ▇▇▇.▇▇ ▇▇▇ ▇ ▇▇ ▇▇▇/▇▇ 2 , ▇▇▇▇▇ ▇ ▇▇▇▇▇▇▇▇▇ Self-organization of the bacterial cell-division protein FtsZ in confined environments† ▇▇▇▇▇ ▇▇▇▇▇▇▇▇,‡a Begon~a ▇▇▇▇▇▇▇▇▇▇,‡b ▇▇▇▇▇▇▇▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇,a Esra ▇▇ ▇▇▇▇▇▇,a ▇▇▇▇▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇▇▇▇▇▇,a Germa´n ▇▇▇▇▇§*b 2 , M I CHAEL OBE R ST EI NER 2 and ▇▇▇▇▇▇▇ ▇. ▇. ▇▇▇▇§*▇▇▇▇▇▇ 1 1Department of Environmental Science, Institute for Water and Wetland Research, Radboud University Nijmegen, P.O. Box 9010, Nijmegen, GL 6500, the Netherlands, 2International Institute of Applied Systems Analysis, Ecosystem Services and Management Program, Laxenburg A-2361, Austria Abstract Biofuels are a We report potentially important source of energy for our society. Common practice in life cycle assessment (LCA) of bioenergy has been to assume that any carbon dioxide (CO2) emission related to biomass combustion equals the amount absorbed in biomass, thus assuming no climate change impacts. Recent developments show the significance of contributions of biogenic CO2 emissions during the time they stay in the atmosphere. The goal of this article is to develop a microfluidic approach global, spatially explicit method to generate aqueous droplets quantify the potential impact on human health and terrestrial ecosystems of biogenic carbon emissions coming from forest wood extraction for biofuel production. For this purpose, changes in oil aboveground carbon stock (DCforest) due to an increase in wood extrac- tion via changes in rotation time are simulated worldwide with a 0.5° 9 0.5° grid resolution. Our results show that both impacts and benefits can be obtained. When the extraction increase is reached by creating a longer rotation time, new growth is allowed resulting in carbon benefits. In a case study, we assessed the life cycle impacts of different dimensionality, stabilized by heat production via wood to determine the significance of including biogenic CO2 emissions due to changes in forest management. Impacts of biogenic CO2 dominate the total climate change impacts from a lipid monolayer, to systematically probe the polymerization of bacterial cell-division protein FtsZ into fibrous networks as a function of the concentrations of crowding agent, FtsZ, and GTPwood stove. FtsZ bundles confined in droplets were dynamic, and their distribution depended Depending on the intrinsic properties of wood source country, climate change impacts due to heat production from wood either have an important share in the system overall impacts on human health and restrictions imposed by the spatial boundariesterrestrial ecosystems, or allow for a large additional CO2 sink.