Common use of Proposed Scope of Work Clause in Contracts

Proposed Scope of Work. This work is an extension of the Development Batch - Inquiry No. 807836c Currently, [ * ] of [ * ] intermediate [ * ] ([ * ]) was prepared and [ * ] shipped to GTx for development work. This proposal consists of splitting the [ * ] into [ * ], synthesis of [ * ], synthesis of [ * ], an additional shipment to GTx Inc., and process development work for [ * ] This proposal does not include final release testing. 1) [ * ]. [ * ] of [ * ] will be used to synthesis [ * ]. The scope includes starting from [ * ] of [ * ] and performing [ * ] to synthesis [ * ] using the best technology available, non-GMP. [ * ] of [ * ] will be shipped to GTx Inc., the remainder will be used in [ * ]. [ * ] will be performed under GMP conditions to yield [ * ]. The targeted amount is [ * ] of [ * ]. [ * ] will require dedicated glassware, estimated to be [ * ]. 2) [ * ]. [ * ] of [ * ] will be used to synthesize [ * ]. Starting with [ * ] of [ * ] should yield approx [ * ] of [ * ] ([ * ] product) non-GMP. The scope of Inquiry number 807836c included [ * ] ([ * ] intermediate, yield approx [ * ]). No additional cost is required for the larger scale in this proposal. [ * ] will be invoiced under Inquiry number 807836c. This current inquiry includes [ * ] performed under GMP conditions to yield [ * ]. The targeted amount is [ * ] of [ * ]. 3) Shipment to GTx [ * ] of [ * ] will be shipped to GTx [ * ]. 4) The remainder [ * ] of [ * ] will be used during Inquiry number 807836c for [ * ] for lab scale development of [ * ].