Common use of REFERENCE VALUES Clause in Contracts

REFERENCE VALUES. The reference value for Plateletworks AA agonist tube was determined on samples collected from healthy volunteers. Each laboratory should establish their own reference range with their normal patient population.6 The data are as follows: AA 60-100% aggregation Plateletworks arachidonic acid aggregation was done on samples from volunteer donors. 134 samples were from individuals not taking aspirin and 265 were from individuals taking aspirin. The results are shown below. Normal (positive) = ≥60% Aggregation Abnormal (negative) = <60% Aggregation Overall Agreement 90.7% Positive Agreement 87.6% Negative Agreement 97.0% - Only fresh, human whole blood should be added to the Plateletworks tubes. Do not collect samples into blood collection tubes containing anticoagulant (i.e., sodium citrate, EDTA, or heparin) prior to addition to the Plateletworks tubes. - It is recognized that many drugs and compounds (prescription and non-prescription) may affect platelet aggregation. The most common of these is aspirin. Therefore, a complete medical history that includes a list of drugs taken for 7-10 days prior to testing should be obtained. - The validity of the Plateletworks assay is dependent on the accuracy of the platelet counts obtained. Multiple factors may potentially interfere with the accuracy of the platelet count when performed on an automated cell counter. Therefore, platelet counts obtained should be scrutinized in light of the patient’s clinical circumstance and previous platelet count results. Plateletworks results should always be interpreted in light of the clinical history and condition of the patient. - It may be beneficial for any abnormal baseline results to be further investigated using additional platelet testing methodology, such as platelet count, bleeding time, assessment of platelet morphology, and others. - Do not use Plateletworks tubes past their expiration date or those which have been improperly stored. - Plateletworks results may be affected by poor technique (e.g., improper blood sample volume, delayed test performance beyond recommended procedure, etc.).

REFERENCE VALUES. The reference value for Plateletworks AA agonist tube was determined on samples collected from healthy volunteers. Each laboratory should establish their own reference range with their normal patient population.6 The data are as follows: AA 60-100% aggregation Plateletworks P lateletworks arachidonic acid aggregation was done on samples from volunteer donors. 134 samples were from individuals not taking aspirin and 265 were from individuals taking aspirin. The results are shown below. Normal (positive) = ≥60% Aggregation Abnormal (negative) = <60% Aggregation Overall Agreement 90.7% Positive Agreement 87.6% Negative Agreement 97.0% - Only fresh, human whole blood should be added to the Plateletworks tubes. Do not collect samples into blood collection tubes containing anticoagulant (i.e., sodium citrate, EDTA, or heparin) prior to addition to the Plateletworks tubes. - It is recognized that many drugs and compounds (prescription and non-prescription) may affect platelet aggregation. The most common of these is aspirin. Therefore, a complete medical history that includes a list of drugs taken for 7-10 days prior to testing should be obtained. - The validity of the Plateletworks assay is dependent on the accuracy of the platelet counts obtained. Multiple factors may potentially interfere with the accuracy of the platelet count when performed on an automated cell counter. Therefore, platelet counts obtained should be scrutinized in light of the patient’s clinical circumstance and previous platelet count results. Plateletworks results should always be interpreted in light of the clinical history and condition of the patient. - It may be beneficial for any abnormal baseline results to be further investigated using additional platelet testing methodology, such as platelet count, bleeding time, assessment of platelet morphology, and others. - Do not use Plateletworks tubes past their expiration date or those which have been improperly stored. - Plateletworks results may be affected by poor technique (e.g., improper blood sample volume, delayed test performance beyond recommended procedure, etc.).