Common use of Scope of Use Clause in Contracts

Scope of Use. 2.1 Subject to the terms of this MTA, Principal Investigator may use the Biological Material during the License Term for the use of Biological Material for non-exclusive research and development purposes, including EV-testing and production of any kind of cell-derived products (e.g. EV’s, RNA, proteins, etc.), excluding the production of clinical grade material, in one Principal Investigator’s laboratory only. Biological Material is not intended for use in humans. LICENSEE agrees that Biological Material designated as biosafety greater than 1 constitute known pathogens and that Biological Material not designated this way may be pathogenic under certain conditions (for further details see PDS). LICENSEE assumes all risk and responsibility in connection with the receipt, handling, storage, disposal, transfer and LICENSEE’s use of the Biological Material including without limitation taking all appropriate safety and handling precautions to minimize health or environmental risk. LICENSEE agrees that any activity undertaken with the Biological Material will be conducted in compliance with all applicable guidelines, laws and regulations, and that LICENSEE will obtain all permits, licenses or other approvals required by any governmental authority in connection with LICENSEE’s receipt, handling, storage, disposal, transfer and use of Biological Material. 2.2 LICENSEE shall not distribute, sell, lend or otherwise transfer, to a person other than the Principal Investigator, or entity not party to this MTA, the Biological Material, as defined above, for any reason, without EVERCYTE’s prior written consent. LICENSEE may not transfer the Biological Material to any Third Parties. LICENSEE agrees that any investigator other than the Principal Investigator utilizing the Biological Material will be required to obtain a separate license. Any licensing of Modifications requires additional rights from EVERCYTE. 2.3 Any Commercial Use of the Biological Material is strictly prohibited without EVERCYTE’s prior written consent. 2.4 Upon termination or expiration of this MTA LICENSEE shall stop to use the Biological Material and LICENSEE shall confirm in writing by authorized persons the destruction of remaining Biological Material(s) in Principal Investigator’s laboratory. The Certificate of Destruction is available online (▇▇▇▇://▇▇▇.▇▇▇▇▇▇▇▇.▇▇▇/certificate-of-destruction) or upon request.

Scope of Use. 2.1 Subject to the terms of this MTA, Principal Investigator may use the Biological Material EVERCYTE Materials provided to Purchaser by EVERCYTE during the License Term for the use of Biological Material for non-exclusive research and development purposes, including EV-testing and production of any kind of cell-derived products (e.g. EV’s, RNA, proteins, etc.), excluding the production of clinical grade material, purposes in one Principal Investigator’s laboratory only. Biological EVERCYTE Material is not intended for use in humans. LICENSEE Purchaser agrees that Biological Material EVERCYTE Materials designated as biosafety greater than 1 constitute known pathogens and that Biological Material EVERCYTE Materials not designated this way may be pathogenic under certain conditions (for further details see PDS). LICENSEE Purchaser assumes all risk and responsibility in connection with the receipt, handling, storage, disposal, transfer and LICENSEEPurchaser’s use of the Biological Material EVERCYTE Materials including without limitation taking all appropriate safety and handling precautions to minimize health or environmental risk. LICENSEE Purchaser agrees that any activity undertaken with the Biological Material EVERCYTE Materials will be conducted in compliance with all applicable guidelines, laws and regulations, and that LICENSEE Purchaser will obtain all permits, licenses or other approvals required by any governmental authority in connection with LICENSEEpurchaser’s receipt, handling, storage, disposal, transfer and use of Biological Materialthe EVERCYTE Materials. 2.2 LICENSEE Purchaser shall not distribute, sell, lend or otherwise transfer, to a person other than the Principal Investigator, or entity not party to this MTA, the Biological EVERCYTE Material, as defined above, for any reason, without EVERCYTE’s prior written consent. LICENSEE Purchaser may not transfer the Biological EVERCYTE Material to any Third Partiesthird parties. LICENSEE Purchaser agrees that any investigator other than the Principal Investigator utilizing the Biological EVERCYTE Material will be required to obtain a separate license. Any licensing of Modifications requires additional rights from EVERCYTE. 2.3 Any Commercial Use of the Biological EVERCYTE Material is strictly prohibited without EVERCYTE’s prior written consent. Purchaser acknowledges and agrees that Purchaser’s use of certain EVERCYTE Material may require a license from a person or entity not party to this MTA or be subject to restrictions that may be imposed by a person or entity not party to this MTA. 2.4 Upon termination or expiration of this MTA LICENSEE Purchaser shall stop to use the Biological Material Evercyte Material(s) and LICENSEE Purchaser shall confirm in writing by authorized persons the destruction of remaining Biological EVERCYTE Material(s) in Principal Investigator’s laboratory. The Certificate of Destruction is available online (▇▇▇▇://▇▇▇.▇▇▇▇▇▇▇▇.▇▇▇/certificate-of-destruction) or upon request.

Scope of Use. 2.1 3.1 Subject to the terms provisions of this MTA, Principal Investigator Purchaser may use the Biological Material MSC(s), Modification(s), Progeny and Unmodified Derivative(s) during the License Term for the use term of Biological Material this MTA for non-exclusive research and development purposes, including EV-testing and production of any kind of cell-derived products (e.g. EV’s, RNA, proteins, etc.), excluding the production of clinical grade material, purposes in one Principal InvestigatorPurchaser’s laboratory only. Biological Material is not intended for MSC (s), Modification(s), Progeny and Unmodified Derivative(s) are strictly prohibited to use in humans, including but not limited, any clinical research and any clinical trial. LICENSEE Purchaser agrees that Biological Material the MSCs designated as biosafety greater than 1 [1] constitute known pathogens and that Biological Material MSC s not designated this way may be pathogenic under certain conditions (for further details see PDSthe Certificate of Analysis (“COA”) and the Product Sheet provided by SPI if any). LICENSEE Purchaser assumes all risk and responsibility in connection with the receipt, handling, storage, disposal, transfer and LICENSEEPurchaser’s use of the Biological Material MSC(s) including without limitation taking all appropriate safety and handling precautions to minimize health or environmental risk. LICENSEE Purchaser agrees that any activity undertaken with the Biological Material MSC (s) will be conducted in compliance with all applicable guidelines, laws and regulations, and that LICENSEE Purchaser will obtain all permits, licenses or other approvals required by any governmental authority in connection with LICENSEEpurchaser’s receipt, handling, storage, disposal, transfer and use of Biological Materialthe MSC(s). 2.2 LICENSEE 3.2 Purchaser shall not distribute, sell, lend or otherwise transfer, to a person other than the Principal Investigatorperson, organization or entity not party to this MTA, the Biological MaterialMSC (s), as defined aboveModification(s), Progeny and/or Unmodified Derivative(s) for any reason, without EVERCYTESPI’s prior written consent. LICENSEE may not transfer the Biological Material to any Third Parties. LICENSEE agrees that any investigator other than the Principal Investigator utilizing the Biological Material will be required to obtain a separate license. Any licensing of Modifications requires additional rights from EVERCYTE. 2.3 Any Commercial Use of the Biological Material is strictly prohibited without EVERCYTE’s prior written consent. 2.4 Upon termination or expiration of this MTA LICENSEE shall stop to use the Biological Material and LICENSEE shall confirm in writing by authorized persons the destruction of remaining Biological Material(s) in Principal Investigator’s laboratory. The Certificate of Destruction is available online (▇▇▇▇://▇▇▇.▇▇▇▇▇▇▇▇▇ agrees that any third party other than the Purchaser utilizing the MSC (s), Modification(s), Progeny and Unmodified Derivative(s) will be required to obtain a prior written agreement separately.▇▇▇/certificate-of-destruction 3.3 Purchaser and SPI shall have discussion separately and determine the specific terms and condition if Purchaser wishes to use MSC (s), Modification(s), Progeny and/or Unmodified Derivative(s) for Commercial Use. Provider and SPI make no representation or upon requestwarranty that the use of the MSC (s), Modification(s), Progeny and/or Unmodified Derivative(s) will not infringe any patent or other proprietary right and regarding the existence or the validity of such rights. Purchaser shall have the sole responsibility for obtaining any intellectual property licenses necessitated by its possession and use of the MSC (s) Modification(s), Progeny and/or Unmodified Derivative(s). 3.4 Upon termination of this MTA, Purchaser shall stop to use MSC (s), Modification(s), Progeny and/or Unmodified Derivative(s). 3.5 SPI is providing Purchaser with MSC (s) pursuant to an agreement by and between Provider and SPI. Provider is an express third party beneficiary of this MTA.

Scope of Use. 2.1 2.1. Subject to the terms of this MTA, Principal Investigator may use the Biological Material during the License Term for the use of Biological Material EVERCYTE Materials provided to Purchaser by EVERCYTE for non-exclusive research and development purposes, including EV-testing and production of any kind of cell-derived products (e.g. EV’s, RNA, proteins, etc.), excluding the production of clinical grade material, purposes in one Principal Investigator’s laboratory only. Biological EVERCYTE Material is not intended for use in humans. LICENSEE Purchaser agrees that Biological Material EVERCYTE Materials designated as biosafety greater than 1 constitute known pathogens and that Biological Material EVERCYTE Materials not designated this way may be pathogenic under certain conditions (for further details see PDS). LICENSEE Purchaser assumes all risk and responsibility in connection with the receipt, handling, storage, disposal, transfer and LICENSEEPurchaser’s use of the Biological Material EVERCYTE Materials including without limitation taking all appropriate safety and handling precautions to minimize health or environmental risk. LICENSEE Purchaser agrees that any activity undertaken with the Biological Material EVERCYTE Materials will be conducted in compliance with all applicable guidelines, laws and regulations, and that LICENSEE Purchaser will obtain all permits, licenses or other approvals required by any governmental authority in connection with LICENSEEpurchaser’s receipt, handling, storage, disposal, transfer and use of Biological Materialthe EVERCYTE Materials. 2.2 LICENSEE 2.2. Purchaser shall not distribute, sell, lend or otherwise transfer, to a person other than the Principal Investigator, or entity not party to this MTA, the Biological EVERCYTE Material, as defined above, for any reason, without EVERCYTE’s prior written consent. LICENSEE Purchaser may not transfer the Biological EVERCYTE Material to any Third Partiesthird parties. LICENSEE Purchaser agrees that any investigator other than the Principal Investigator utilizing the Biological EVERCYTE Material will be required to obtain a separate license. Any licensing of Modifications requires additional rights from EVERCYTE. 2.3 2.3. Any Commercial Use of the Biological EVERCYTE Material is strictly prohibited without EVERCYTE’s prior written consent. Purchaser acknowledges and agrees that Purchaser’s use of certain EVERCYTE Material may require a license from a person or entity not party to this MTA or be subject to restrictions that may be imposed by a person or entity not party to this MTA. 2.4 2.4. Upon termination or expiration of this MTA LICENSEE Purchaser shall stop to use the Biological Material Evercyte Material(s) and LICENSEE Purchaser shall confirm in writing by authorized persons the destruction of remaining Biological EVERCYTE Material(s) in Principal Investigator’s laboratory. The Certificate of Destruction is available online (▇▇▇▇://▇▇▇.▇▇▇▇▇▇▇▇.▇▇▇/certificate-of-destruction) or upon request.

Scope of Use. 2.1 3.1 Subject to the terms provisions of this MTA, Principal Investigator Purchaser may use the Biological Material MSC(s), Modification(s), Progeny and Unmodified Derivative(s) during the License Term for the use term of Biological Material this MTA for non-exclusive research and development purposes, including EV-testing and production of any kind of cell-derived products (e.g. EV’s, RNA, proteins, etc.), excluding the production of clinical grade material, purposes in one Principal InvestigatorPurchaser’s laboratory only. Biological Material is not intended for MSC(s), Modification(s), Progeny and Unmodified Derivative(s) are strictly prohibited to use in humans, including but not limited, any clinical research and any clinical trial. LICENSEE Purchaser agrees that Biological Material the MSCs designated as biosafety greater than 1 [1] constitute known pathogens and that Biological Material MSCs not designated this way may be pathogenic under certain conditions (for further details see PDSthe Certificate of Analysis (“COA”) and the Product Sheet provided by SPI if any). LICENSEE Purchaser assumes all risk and responsibility in connection with the receipt, handling, storage, disposal, transfer and LICENSEEPurchaser’s use of the Biological Material MSC(s) including without limitation taking all appropriate safety and handling precautions to minimize health or environmental risk. LICENSEE Purchaser agrees that any activity undertaken with the Biological Material MSC(s) will be conducted in compliance with all applicable guidelines, laws and regulations, and that LICENSEE Purchaser will obtain all permits, licenses or other approvals required by any governmental authority in connection with LICENSEEpurchaser’s receipt, handling, storage, disposal, transfer and use of Biological Materialthe MSC(s). 2.2 LICENSEE 3.2 Purchaser shall not distribute, sell, lend or otherwise transfer, to a person other than the Principal Investigatorperson, organization or entity not party to this MTA, the Biological MaterialMSC(s), as defined aboveModification(s), Progeny and/or Unmodified Derivative(s) for any reason, without EVERCYTESPI’s prior written consent. LICENSEE may not transfer the Biological Material to any Third Parties. LICENSEE Purchaser agrees that any investigator third party other than the Principal Investigator Purchaser utilizing the Biological Material MSC(s), Modification(s), Progeny and Unmodified Derivative(s) will be required to obtain a separate license. Any licensing of Modifications requires additional rights from EVERCYTEprior written agreement separately. 2.3 Any 3.3 Purchaser and SPI shall have discussion separately and determine the specific terms and condition if Purchaser wishes to use MSC(s), Modification(s), Progeny and/or Unmodified Derivative(s) for Commercial Use Use. Provider and SPI make no representation or warranty that the use of the Biological Material is strictly prohibited without EVERCYTE’s prior written consentMSC(s), Modification(s), Progeny and/or Unmodified Derivative(s) will not infringe any patent or other proprietary right and regarding the existence or the validity of such rights. Purchaser shall have the sole responsibility for obtaining any intellectual property licenses necessitated by its possession and use of the MSC(s) Modification(s), Progeny and/or Unmodified Derivative(s). 2.4 3.4 Upon termination or expiration of this MTA LICENSEE MTA, Purchaser shall stop to use the Biological Material MSC(s), Modification(s), Progeny and/or Unmodified Derivative(s). 3.5 SPI is providing Purchaser with MSC(s) pursuant to an agreement by and LICENSEE shall confirm in writing by authorized persons the destruction between Provider and SPI. Provider is an express third party beneficiary of remaining Biological Material(s) in Principal Investigator’s laboratory. The Certificate of Destruction is available online (▇▇▇▇://▇▇▇this MTA .▇▇▇▇▇▇▇▇.▇▇▇/certificate-of-destruction) or upon request.

Scope of Use. 2.1 3.1 Subject to the terms provisions of this MTA, Principal Investigator Purchaser may use the Biological Material MSC(s), Modification(s), Progeny and Unmodified Derivative(s) during the License Term for the use term of Biological Material this MTA for non-exclusive research and development purposes, including EV-testing and production of any kind of cell-derived products (e.g. EV’s, RNA, proteins, etc.), excluding the production of clinical grade material, purposes in one Principal InvestigatorPurchaser’s laboratory only. Biological Material is not intended for MSC(s), Modification(s), Progeny and Unmodified Derivative(s) are strictly prohibited to use in humans, including but not limited, any clinical research and any clinical trial. LICENSEE Purchaser agrees that Biological Material the MSCs designated as biosafety greater than 1 [1] constitute known pathogens and that Biological Material MSCs not designated this way may be pathogenic under certain conditions (for further details see PDSthe Certificate of Analysis (“COA”) and the Product Sheet provided by SPI if any). LICENSEE Purchaser assumes all risk and responsibility in connection with the receipt, handling, storage, disposal, transfer and LICENSEEPurchaser’s use of the Biological Material MSC(s) including without limitation taking all appropriate safety and handling precautions to minimize health or environmental risk. LICENSEE Purchaser agrees that any activity undertaken with the Biological Material MSC(s) will be conducted in compliance with all applicable guidelines, laws and regulations, and that LICENSEE Purchaser will obtain all permits, licenses or other approvals required by any governmental authority in connection with LICENSEEpurchaser’s receipt, handling, storage, disposal, transfer and use of Biological Materialthe MSC(s). 2.2 LICENSEE 3.2 Purchaser shall not distribute, sell, lend or otherwise transfer, to a person other than the Principal Investigatorperson, organization or entity not party to this MTA, the Biological MaterialMSC(s), as defined aboveModification(s), Progeny and/or Unmodified Derivative(s) for any reason, without EVERCYTESPI’s prior written consent. LICENSEE may not transfer the Biological Material to any Third Parties. LICENSEE Purchaser agrees that any investigator third party other than the Principal Investigator Purchaser utilizing the Biological Material MSC(s), Modification(s), Progeny and Unmodified Derivative(s) will be required to obtain a separate license. Any licensing of Modifications requires additional rights from EVERCYTEprior written agreement separately. 2.3 Any 3.3 Purchaser and SPI shall have discussion separately and determine the specific terms and condition if Purchase wishes to use MSC(s), Modification(s), Progeny and/or Unmodified Derivative(s) for Commercial Use Use. Provider and SPI make no representation or warranty that the use of the Biological Material is strictly prohibited without EVERCYTE’s prior written consent.MSC(s), Modification(s), Progeny and/or Unmodified Derivative(s) will not infringe any patent or other proprietary right and regarding the existence or the validity of such rights. Purchaser shall have the sole responsibility for obtaining any intellectual property licenses necessitated by its 2.4 3.4 Upon termination or expiration of this MTA LICENSEE MTA, Purchaser shall stop to use the Biological Material MSC(s), Modification(s), Progeny and/or Unmodified Derivative(s). 3.5 SPI is providing Purchaser with MSC(s) pursuant to an agreement by and LICENSEE shall confirm in writing by authorized persons the destruction between Provider and SPI. Provider is an express third party beneficiary of remaining Biological Material(s) in Principal Investigator’s laboratory. The Certificate of Destruction is available online (▇▇▇▇://▇▇▇this Agreement.▇▇▇▇▇▇▇▇.▇▇▇/certificate-of-destruction) or upon request.

Scope of Use. 2.1 2.1. Subject to the terms of this MTA, Principal Investigator investigator may use the Biological Material during the License Term for the use of Biological Material EVERCYTE Materials provided to Purchaser by EVERCYTE for non-exclusive research and development purposes, including EV-testing and production of any kind of cell-derived products (e.g. EV’s, RNA, proteins, etc.), excluding the production of clinical grade material, purposes in one Principal Investigator’s laboratory only. Biological EVERCYTE Material is not intended for use in humans. LICENSEE Purchaser agrees that Biological Material EVERCYTE Materials designated as biosafety greater than 1 constitute known pathogens and that Biological Material EVERCYTE Materials not designated this way may be pathogenic under certain conditions (for further details see PDS). LICENSEE Purchaser assumes all risk and responsibility in connection with the receipt, handling, storage, disposal, transfer and LICENSEEPurchaser’s use of the Biological Material EVERCYTE Materials including without limitation taking all appropriate safety and handling precautions to minimize health or environmental risk. LICENSEE Purchaser agrees that any activity undertaken with the Biological Material EVERCYTE Materials will be conducted in compliance with all applicable guidelines, laws and regulations, and that LICENSEE Purchaser will obtain all permits, licenses or other approvals required by any governmental authority in connection with LICENSEEpurchaser’s receipt, handling, storage, disposal, transfer and use of Biological Materialthe EVERCYTE Materials. 2.2 LICENSEE 2.2. Purchaser shall not distribute, sell, lend or otherwise transfer, to a person other than the Principal Investigator, or entity not party to this MTA, the Biological EVERCYTE Material, as defined above, for any reason, without EVERCYTE’s prior written consent. LICENSEE Purchaser may not transfer the Biological EVERCYTE Material to any Third Partiesthird parties. LICENSEE Purchaser agrees that any investigator other than the Principal Investigator utilizing the Biological EVERCYTE Material will be required to obtain a separate license. Any licensing of Modifications requires additional rights from EVERCYTE. 2.3 2.3. Any Commercial Use of the Biological EVERCYTE Material is strictly prohibited without EVERCYTE’s prior written consent. Purchaser acknowledges and agrees that Purchaser’s use of certain EVERCYTE Material may require a license from a person or entity not party to this MTA or be subject to restrictions that may be imposed by a person or entity not party to this MTA. 2.4 2.4. Upon termination or expiration of this MTA LICENSEE Purchaser shall stop to use the Biological Material Evercyte Material(s) Purchaser and LICENSEE shall confirm in writing by authorized persons the destruction of remaining Biological EVERCYTE Material(s) in Principal Investigator’s laboratory. The Certificate of Destruction is available online (▇▇▇▇://▇▇▇.▇▇▇▇▇▇▇▇.▇▇▇/certificate-of-destruction) or upon request.

Scope of Use. 2.1 2.1. Subject to the terms of this MTA, Principal Investigator investigator may use the Biological Material during the License Term for the use of Biological Material EVERCYTE Materials provided to Purchaser by EVERCYTE for non-exclusive research and development purposes, including EV-testing and production of any kind of cell-derived products (e.g. EV’s, RNA, proteins, etc.), excluding the production of clinical grade material, purposes in one Principal Investigator’s laboratory only. Biological EVERCYTE Material is not intended for use in humans. LICENSEE Purchaser agrees that Biological Material EVERCYTE Materials designated as biosafety greater than 1 constitute known pathogens and that Biological Material EVERCYTE Materials not designated this way may be pathogenic under certain conditions (for further details see PDS). LICENSEE Purchaser assumes all risk and responsibility in connection with the receipt, handling, storage, disposal, transfer and LICENSEEPurchaser’s use of the Biological Material EVERCYTE Materials including without limitation taking all appropriate safety and handling precautions to minimize health or environmental risk. LICENSEE Purchaser agrees that any activity undertaken with the Biological Material EVERCYTE Materials will be conducted in compliance with all applicable guidelines, laws and regulations, and that LICENSEE Purchaser will obtain all permits, licenses or other approvals required by any governmental authority in connection with LICENSEEpurchaser’s receipt, handling, storage, disposal, transfer and use of Biological Materialthe EVERCYTE Materials. 2.2 LICENSEE 2.2. Purchaser shall not distribute, sell, lend or otherwise transfer, to a person other than the Principal Investigator, or entity not party to this MTA, the Biological EVERCYTE Material, as defined above, for any reason, without EVERCYTE’s prior written consent. LICENSEE Purchaser may not transfer the Biological EVERCYTE Material to any Third Partiesthird parties. LICENSEE Purchaser agrees that any investigator other than the Principal Investigator utilizing the Biological EVERCYTE Material will be required to obtain a separate license. Any licensing of Modifications requires additional rights from EVERCYTE. 2.3 2.3. Any Commercial Use of the Biological EVERCYTE Material is strictly prohibited without EVERCYTE’s prior written consent. Purchaser acknowledges and agrees that Purchaser’s use of certain EVERCYTE Material may require a license from a person or entity not party to this MTA or be subject to restrictions that may be imposed by a person or entity not party to this MTA. 2.4 2.4. Upon termination or expiration of this MTA LICENSEE Purchaser shall stop to use the Biological Material Evercyte Material(s) and LICENSEE Purchaser shall confirm in writing by authorized persons the destruction of remaining Biological EVERCYTE Material(s) in Principal Investigator’s laboratory. The Certificate of Destruction is available online (▇▇▇▇://▇▇▇.▇▇▇▇▇▇▇▇.▇▇▇/certificate-of-destruction) or upon request.