Common use of Study Termination Clause in Contracts

Study Termination. The study may be prematurely terminated at any time at the discretion of Tonix, its designee, or the Principal Investigator. Should premature termination be considered necessary, written notification documenting the reason for study termination will be provided, and specific procedures for termination will be arranged. Circumstances that may warrant premature study termination include, but are not limited to, the following. • Determination of unexpected, significant, or unacceptable risk to patients • Failure to enter patients at an acceptable rate • Insufficient adherence to the requirements of the protocol • Insufficient provision of complete and evaluable data • Plans to modify, suspend, or discontinue development of the study drug In the event that the study is terminated prematurely, all study materials must be returned to Tonix or its designee.

Study Termination. The study may be prematurely terminated at any time at the discretion of Tonix, its designee, or the Principal Investigatorprincipal investigator. Should premature termination be considered necessary, written notification documenting the reason for study termination will be provided, and specific procedures for termination will be arranged. Circumstances that may warrant premature study termination include, but are not limited to, the following. • Determination of unexpected, significant, or unacceptable risk to patients • Failure to enter patients at an acceptable rate • Insufficient adherence to the requirements of the protocol • Insufficient provision of complete and evaluable data • Plans to modify, suspend, or discontinue development of the study drug In the event that the study is terminated prematurely, all study materials must be returned to Tonix or its designee.