Exhibit 10.1
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                         ASSET PURCHASE OPTION AGREEMENT
                                 BY AND BETWEEN
                       PROTEIN POLYMER TECHNOLOGIES, INC.
                                       and
                               SURGICA CORPORATION
                                November 23, 2005
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                         ASSET PURCHASE OPTION AGREEMENT
         THIS ASSET PURCHASE  OPTION  AGREEMENT  (this  "Agreement") is made and
entered  into as of  November  23, 2005 by and between  Surgica  Corporation,  a
Delaware corporation (the "Company") and Protein Polymer  Technologies,  Inc., a
Delaware  corporation (the  "Optionee").  Unless otherwise  defined herein,  all
capitalized  terms used  herein  shall  have the  respective  meanings  ascribed
thereto in the Purchase Agreement (defined below).
                                 R E C I T A L S
         WHEREAS,  the  Company  and the  Optionee  propose  to enter  into that
certain  License  Agreement  and that  certain  Supply and  Services  Agreement,
attached  hereto as Exhibit A and  Exhibit B,  respectively  (collectively,  the
"License Agreement"),  pursuant to which the Company,  among other things, would
license to Optionee certain  intellectual  property (including patent and patent
applications), as well as marketing and distribution rights;
         WHEREAS,  in order to induce the  Optionee  to enter  into the  License
Agreement  and to advance funds to the Company,  pursuant to this  Agreement and
subject to the terms herein,  the Optionee shall have the right to purchase from
the  Company  substantially  all of the assets of the  Company  now  existing or
hereafter  acquired  through  the date of the  exercise  of the Option  (defined
below) (the  "Assets") for the purchase  price  described in Section 1.4 of this
Agreement.
         NOW,  THEREFORE,  in consideration of the premises and mutual covenants
and agreements  herein set forth and for other good and valuable  consideration,
the receipt and adequacy of which are hereby  acknowledged,  each of the parties
hereto (individually,  a "Party",  collectively,  the "Parties") hereby agree as
follows:
                                    ARTICLE I
                               OPTION TO PURCHASE
         Section 1.1.  Option to Purchase Assets.
         ---------------------------------------
         Subject to the  satisfaction  or waiver of the  conditions set forth in
Article V hereof,  the Company  hereby grants to Optionee the option to purchase
substantially  all of the Assets  (the  "Option")  during the Option  Period (as
defined in Section 1.2 of this Agreement),  as the same may be extended pursuant
to the terms  hereof,  or such later date as the Parties  shall  mutually  agree
upon.  The date on which the Option  becomes  effective is referred to herein as
the "Option Effective Date."
                                       -1-
         Section 1.2.  The Option Period.
         -------------------------------
         The "Option  Period" shall commence on the date hereof and extend until
One (1) year from the Effective  Date,  provided that,  upon written notice from
Optionee to the Company not more than 60 days and not less than 30 days prior to
such  date,  the  Option  Period  may be  extended  until Two (2) years from the
Effective Date, in the sole and absolute discretion of Optionee.
         Section 1.3.  Exercise of Option.
         --------------------------------
         (a) During the Option  Period,  Optionee  may  exercise the Option only
upon written  notice (the "Option  Notice") to the Company,  in accordance  with
Section 7.7 herein.
         (b) Within 10 days after the Optionee  delivers the Option Notice,  the
Optionee,  Optionee's wholly-owned subsidiary and the Company, must enter into a
definitive asset purchase agreement in substantially the form attached hereto as
Exhibit C (the "Purchase Agreement").
         Section 1.4.  Option Payment.
         ----------------------------
         The  consideration  which  shall be paid by Optionee to the Company for
the  Assets  shall be equal to that set  forth in  Section  2.6 of the  Purchase
Agreement.
         Section 1.5.  Option Closing.
         ----------------------------
         The Option shall become effective (the "Option  Closing") on the Option
Effective Date, which shall be one Business Day after  satisfaction or waiver of
all the  conditions  set forth in Article V hereof,  but in no event  later than
December  17,  2005.  At the Option  Closing,  the parties  shall enter into the
License  Agreement  and Supply and  Services  Agreement  and shall  execute  and
deliver such other instruments and documents contemplated by Article V hereof.
                                   ARTICLE II
                  REPRESENTATIONS AND WARRANTIES OF THE COMPANY
         The Company  represents  and  warrants to the  Optionee for its benefit
that the statements  contained in this Article II are true and correct,  subject
to such  exceptions as are  specifically  disclosed in writing in the Disclosure
Schedule provided by the Company to the Optionee (the "Disclosure Schedule").
         Section 2.1.  Organization, Qualification and Corporate Power.
         -------------------------------------------------------------
         The Company is a corporation  duly organized,  validly  existing and in
corporate good standing under the laws of the State of Delaware.  The Company is
duly  qualified to conduct  business and is in corporate good standing under the
                                       -2-
laws of each jurisdiction in which the nature of its businesses or the ownership
or leasing of its  properties  requires  such  qualification,  except  where the
failure to be so qualified or in good standing would not have a Material Adverse
Effect on the  Company.  The Company has the  corporate  power and  authority to
carry on the businesses in which it is engaged and to own and use the properties
owned  and used by it.  The  Company  has  furnished  or made  available  to the
Optionee  true and  complete  copies of its  Certificate  of  Incorporation  and
Bylaws,  each as amended  and/or  restated  and as in effect on the date  hereof
(hereinafter  the "Charter" and "Bylaws,"  respectively).  The Company is not in
default under or in violation of any provision of its Charter or Bylaws, each as
amended to date.
         Section 2.2.  Representations and Warranties in Purchase Agreement.
         ------------------------------------------------------------------
         The representations  and warranties  regarding the Company set forth in
Article  III of the  Purchase  Agreement  are  true and  correct  as of the date
hereof.
         Section 2.3.  Authorization of Transaction.
         ------------------------------------------
         Subject to the  Requisite  Stockholder  Approval (as defined  below) of
this Agreement, the Company has the corporate power and authority to execute and
deliver this Agreement and to perform its obligations  hereunder.  The execution
and delivery of this Agreement and,  subject to the adoption of this  Agreement,
the proper notice or waiver thereof to the Company's  preferred  stockholders as
provided  in the  Charter  and Bylaws of the  Company  and the  approval  of the
transaction by a majority of the votes represented by the outstanding  shares of
stock entitled to vote on this  Agreement,  which is a majority of the Company's
common stock and preferred  stock voting as a single  class,  with the preferred
voting on an "as converted" basis,  voting in accordance with the corporate laws
of the  State of  Delaware  and the  Charter  and  Bylaws  of the  Company  (the
"Requisite  Stockholder  Approval"),  the  performance  by the  Company  of this
Agreement and the consummation by the Company of the  transactions  contemplated
hereby have been duly and validly  authorized by all necessary  corporate action
on the part of the Company.  This  Agreement has been duly and validly  executed
and delivered by the Company and, assuming the due authorization,  execution and
delivery by the  Optionee,  constitutes  a valid and binding  obligation  of the
Company, enforceable against the Company in accordance with its terms, except as
enforcement  may be limited by bankruptcy,  insolvency,  fraudulent  conveyance,
reorganization,  moratorium and other similar laws affecting the  enforcement of
creditors'  rights  generally,  and except that the  availability  of  equitable
remedies,  including specific  performance,  is subject to the discretion of the
court before which any proceeding therefor may be brought.
         Section 2.4.  Noncontravention.
         ------------------------------
         Subject  to  receipt  of the  Requisite  Stockholder  Approval  and the
consent  of  AngioDynamics,  Inc.,  substantially  in the  form as set  forth on
Exhibit  D,  attached  hereto,  except as set forth on  Schedule  2.4,  attached
hereto, neither the execution and delivery of this Agreement by the Company, nor
the consummation by the Company of the transactions  contemplated  hereby, will:
(a)  conflict  with or violate  any  provision  of the  Charter or Bylaws of the
Company;  (b) require on the part of the Company any filing with, or any permit,
authorization, consent or approval of, any Governmental Body; (c) conflict with,
                                       -3-
result in a breach of,  constitute  (with or without due notice or lapse of time
or both) a default under, result in the acceleration of, create in any party the
right to accelerate, terminate, modify or cancel, or require any notice, consent
or waiver under, any contract, lease, sublease, license, sublicense,  franchise,
permit,  indenture,  agreement  or mortgage for borrowed  money,  instrument  of
indebtedness,  Lien or other  arrangement  to which the Company is a party or by
which the Company is bound or to which any of its Assets is subject;  (d) result
in the imposition of any Lien upon any Assets of the Company; or (e) violate any
order, writ, injunction,  decree,  statute, rule or regulation applicable to the
Company, any of its properties or Assets.
         Section 2.5.  Subsidiaries.
         --------------------------
         The Company  does not have any direct or indirect  subsidiaries  or any
other  equity  interest  in any  other  firm,  corporation,  partnership,  joint
venture, association or other business organization.
         Section 2.6.  Absence of Certain Changes.
         ----------------------------------------
         Since June 30,  2005,  the Company has  conducted  its  business in the
Ordinary  Course of Business  and there has not  occurred  any change,  event or
condition  (whether or not covered by insurance)  that has resulted in, or might
reasonably be expected to result in any material  adverse  change in the Assets,
business, financial condition or results of operations of the Company.
         Section 2.7.  Powers of Attorney.
         --------------------------------
         There are no outstanding  powers of attorney  executed on behalf of the
Company.
         Section 2.8.  Fees.
         ------------------
         Except as  disclosed  in Schedule  2.8, the Company has no liability or
obligation  to pay any fees or  commissions  to any broker,  investment  banking
firm,  finder or agent with  respect to the  transactions  contemplated  by this
Agreement.
         Section 2.9.  Books and Records.
         -------------------------------
         The minute books and other similar  records of the Company contain true
and  complete  records of all  material  actions  taken at any  meetings  of the
stockholders of the Company,  Board of Directors or any committee thereof and of
all written consents executed in lieu of the holding of any such meeting.
         Section 2.10.  Company Action.
         -----------------------------
         The Board of  Directors  of the  Company,  at a meeting duly called and
held,  has by the  unanimous  vote of all  directors  (i)  determined  that  the
transaction contemplated herein is fair and in the best interests of the Company
and its  stockholders,  (ii)  adopted  this  Agreement  in  accordance  with the
provisions of the corporate  laws of the State of Delaware,  and (iii)  directed
that this  Agreement be submitted to the  stockholders  of the Company for their
                                       -4-
adoption and approval and  resolved to recommend  that the  stockholders  of the
Company vote in favor of the adoption of this Agreement.
         Section 2.11.  Disclosure.
         -------------------------
         No  representation  or  warranty  by  the  Company  contained  in  this
Agreement,  and no statement  contained in the Disclosure  Schedule or any other
document,  certificate or other instrument delivered to or to be delivered by or
on behalf  of the  Company  pursuant  to this  Agreement,  contains  any  untrue
statement of a material fact or omits to state any material fact  necessary,  in
light  of the  circumstances  under  which  it was  made,  in  order to make the
statements herein not misleading.
                                   ARTICLE III
                 REPRESENTATIONS AND WARRANTIES OF THE OPTIONEE
                The Optionee represents and warrants to the Company as follows:
         Section 3.1.  Organization.
         --------------------------
         The Optionee is a corporation  duly organized,  validly existing and in
good  standing  under the laws of the state of  Delaware.  The  Optionee is duly
qualified to conduct  business and is in corporate  good standing under the laws
of each  jurisdiction  in which the nature of its businesses or the ownership or
leasing of its properties requires such qualification,  except where the failure
to be so qualified or in good standing would not have a Material  Adverse Effect
on it.
         Section 3.2.  Authorization of Transaction.
         ------------------------------------------
         The Optionee has all corporate requisite power and authority to execute
and  deliver  this  Agreement  and to  perform  its  obligations  hereunder  and
thereunder.  The execution and delivery of this Agreement and the performance of
this Agreement and the consummation of the transactions  contemplated hereby and
thereby by the Optionee  have been duly and validly  authorized by all necessary
corporate  action on the part of the Optionee.  This Agreement has been duly and
validly   executed  and  delivered  by  the  Optionee  and,   assuming  the  due
authorization,  execution  and delivery by the Company,  constitutes a valid and
binding  obligation of the Optionee,  enforceable  against it in accordance with
its terms,  except as enforcement  may be limited by  bankruptcy,  insolvency or
other similar laws affecting the enforcement of creditors' rights generally, and
except  that  the  availability  of  equitable   remedies,   including  specific
performance,  is  subject  to the  discretion  of the  court  before  which  any
proceeding therefor may be brought.
         Section 3.3.  Noncontravention.
         ------------------------------
         Neither  the  execution  and  delivery  of  this  Agreement,   nor  the
consummation by the Optionee of the transactions  contemplated  hereby, will (a)
conflict or violate any provision of the Certificate of  Incorporation or Bylaws
                                       -5-
of the Optionee,  (b) conflict with,  result in breach of,  constitute  (with or
without  due  notice  or lapse of time or both) a default  under,  result in the
acceleration of, create in any party any right to accelerate,  terminate, modify
or cancel, or require any notice, consent or waiver under, any contract,  lease,
sublease,  license,  sublicense,  franchise,  permit,  indenture,  agreement  or
mortgage for borrowed money,  instrument of indebtedness,  security  interest or
other  arrangement  to which the Optionee is a party or by which either is bound
or to which any of their  assets are  subject,  or (c) violate any order,  writ,
injunction,  decree,  statute,  rule or regulation applicable to the Optionee or
any of its properties or assets.
         Section 3.4.  Company Action.
         ----------------------------
         The Board of  Directors of the  Optionee,  at a meeting duly called and
held, have (i) determined that the transaction  contemplated  herein is fair and
in the best  interests of the Optionee  and each of its  stockholders,  and (ii)
adopted this Agreement in accordance with the provisions of the Delaware General
Corporation Law.
         Section 3.5.  Brokers' Fees.
         ---------------------------
         The  Optionee  has no  liability  or  obligation  to pay  any  fees  or
commissions  to any  broker,  finder or agent with  respect to the  transactions
contemplated by this Agreement.
         Section 3.6.  Financial Reports and SEC Documents.
         -------------------------------------------------
         The  Optionee's  Annual Report on Form 10-KSB for the fiscal year ended
December 31, 2004,  as amended by Form 10-KSB/A  filed on May 18, 2005,  and all
other reports, definitive proxy statements or information statements filed or to
be filed by it subsequent to December 31, 2004 under Section 13(a), 13(c), 14 or
15(d) of the Exchange Act in the form filed or to be filed  (collectively,  "SEC
Documents")  with the SEC, as of the date filed or to be filed,  (A) complied or
will comply in all material respects as to form with the applicable requirements
under the Exchange Act and (B) as of the time filed, or to be filed, did not and
will not  contain  any untrue  statement  of a material  fact or omit to state a
material fact required to be stated  therein or necessary to make the statements
therein,  in the light of the  circumstances  under  which they were  made,  not
misleading;  and each of the balance  sheets  contained  in or  incorporated  by
reference into any such SEC Document  (including the related notes and schedules
thereto)  fairly  presents,  or will fairly present,  the financial  position of
Optionee  and  its  subsidiaries,  if  any,  as of its  date,  and  each  of the
statements  of income  and  changes  in  shareholders'  equity and cash flows or
equivalent  statements  in such SEC Documents  (including  any related notes and
schedules  thereto)  fairly  presents,  or will fairly  present,  the results of
operations,  changes in  shareholders'  equity and changes in cash flows, as the
case may be, of Optionee and its subsidiaries,  if any, for the periods to which
they relate,  in each case in  accordance  with U.S. GAAP  consistently  applied
during  the  periods  involved,  except  in each  case as may be noted  therein,
subject to the absence of footnotes and to normal  year-end  adjustments  in the
case of unaudited statements.
                                       -6-
                                   ARTICLE IV
                    COVENANTS BY THE OPTIONEE AND THE COMPANY
                The Optionee and the Company covenant as follows:
         Section 4.1.  Satisfaction of Conditions.
         ----------------------------------------
         Each of the Parties shall use its  commercially  reasonable  efforts to
take all actions and to do all things necessary,  proper or advisable to satisfy
the conditions set forth in Article V of this Agreement.
         Section 4.2.  Notices and Consents.
         ----------------------------------
         Each of the  Optionee  and the  Company  shall use  their  commercially
reasonable  efforts  to  obtain,  at its  expense,  all such  waivers,  permits,
consents,  approvals or other authorizations from third parties and Governmental
Bodies,  and to effect all such  registrations,  filings and notices  with or to
third parties and Governmental  Bodies, as may be required by or with respect to
the Optionee or the Company,  respectively,  in connection with the transactions
contemplated by this Agreement.
         Section 4.3.  Operation of Business.
         -----------------------------------
         Except as contemplated  by this  Agreement,  during the period from the
date of this  Agreement  up until the Closing  Date (as defined in the  Purchase
Agreement),  the Company shall conduct its operations in the Ordinary  Course of
Business and in compliance with all applicable laws and regulations  and, to the
extent consistent  therewith,  use all reasonable efforts to preserve intact its
current  business  organization,  keep  its  physical  Assets  in  good  working
condition, keep available the services of its current officers and employees and
preserve its relationships with customers,  suppliers and others having business
dealings with it to the end that its goodwill and ongoing  business shall not be
impaired  in any  material  respect.  Without  limiting  the  generality  of the
foregoing, prior to the Closing Date, the Company shall not, without the written
consent of the Optionee:
         (a) issue,  sell,  deliver or agree or commit to issue, sell or deliver
(whether  through the  issuance or granting of options,  warrants,  commitments,
subscriptions,  rights to purchase or otherwise) or authorize the issuance, sale
or  delivery  of, or redeem or  repurchase,  any stock of any class or any other
securities or any rights, warrants or options to acquire any such stock or other
securities  (except  pursuant  to the  conversion  or  exercise  of  convertible
securities, options or warrants outstanding on the date hereof), or amend any of
the terms of any such convertible securities, options or warrants;
         (b) split,  combine or  reclassify  any  shares of its  capital  stock;
declare,  set aside or pay any  dividend,  special  bonus or other  distribution
(whether in cash,  stock or property or any  combination  thereof) in respect of
its capital stock;
                                       -7-
         (c)  create,  incur  or  assume  any  debt  not  currently  outstanding
(including obligations in respect of capital leases); assume, guarantee, endorse
or otherwise  become liable or responsible  (whether  directly,  contingently or
otherwise) for the obligations of any other person or entity; or make any loans,
advances or capital  contributions to, or investments in, or increase the amount
of any existing loan to any other person or entity;
         (d) enter into, adopt or amend any Plans or any employment or severance
agreement or  arrangement or increase in any manner the  compensation  or fringe
benefits  of, or modify the  employment  terms of, its  directors,  officers  or
employees,  generally  or  individually,  or pay any benefit not required by the
terms in effect on the date hereof of any existing Plan;
         (e)  acquire,  sell,  transfer,  lease,  sublease,   license,  abandon,
encumber,  transfer or  otherwise  dispose of any  properties  or assets,  real,
personal  or mixed  (including  leasehold  interests  and  intangible  property)
related to the Operations, except in the Ordinary Course of Business
         (f) amend and/or restate its Charter or Bylaws;
         (g) change in any material respect its accounting  methods,  principles
or practices,  or make any change in depreciation  or  amortization  policies or
lives adopted by it except insofar as may be required by a generally  applicable
change in GAAP or as required by Optionee;
         (h)  discharge or satisfy any Lien or pay any  obligation  or liability
other than in the Ordinary Course of Business;
         (i) settle,  compromise,  materially modify or amend, waive, terminate,
cancel, release or assign any rights or Claims concerning, affecting or relating
to any Contract relating to the Operations (including,  without limitation,  any
Assigned Agreement), or otherwise relating to the Operations;
         (j)  mortgage  or pledge any of its  property  or Assets or subject any
such Assets to any Lien;
         (k) sell, assign, license, grant or transfer any rights under, or enter
into any settlement  regarding the breach or infringement  of, any  Intellectual
Property, or modify any existing rights with respect thereto;
         (l) enter into, amend, terminate,  take or omit to take any action that
would  constitute a violation of or default under,  or waive,  release or assign
any rights under, any contract or agreement;
         (m) enter  into,  amend,  modify or consent to the  termination  of any
Assigned Agreement;
                                       -8-
         (n) make or commit to make any  capital  expenditure  in excess of Five
Thousand Dollars ($5,000) per item;
         (o)  take  any  action  or fail to take any  action  permitted  by this
Agreement  with the  knowledge  that such action or failure to take action would
result in (i) any of the representations and warranties of the Company set forth
in this Agreement or the Purchase  Agreement  becoming untrue or (ii) any of the
conditions to the transaction set forth in Article V, not being satisfied;
         (p) make any material charitable contribution;
         (q) engage or terminate any consultant;
         (r) enter into,  materially  amend or (except in  conjunction  with the
completion of the term thereof)  terminate any Contract or transaction  with any
director or officer,  stockholder  or Affiliate of Seller (or with any relative,
beneficiary, spouse or Affiliate of such Person) relating to the Operations;
         (s) terminate,  discontinue,  close or dispose of any facility or other
business operation,  or lay off any employees or implement any early retirement,
separation or program  providing early retirement window benefits or announce or
plan any such action or program for the future;
         (t) allow any Permit  that was issued or relates to the  Operations  to
lapse or  terminate  or fail to renew any  insurance  policy  or Permit  that is
scheduled  to terminate or expire  within forty five (45)  calendar  days of the
Effective  Date,  except to the extent that such failure would not be reasonably
expected to cause a Material Adverse Effect on the ability of the Company to own
and operate the Operations as now conducted;
         (u) enter  into any  contract,  other  than in the  Ordinary  Course of
Business and as provided to the Optionee, or any amendment or termination of, or
default  under,  any  contract  that is or was  material  to the  Operations  or
Seller's rights thereunder;
         (v) commence any litigation  other than (i) for the routine  collection
of bills or (ii) in such cases where the Company in good faith  determines  that
failure to commence  suit would result in the material  impairment of a valuable
aspect of the  Company's  business,  provided  that  Company  consults  with the
Optionee prior to the filing of such a suit;
         (w) make or change any material election in respect of Taxes,  adopt or
change any accounting  method in respect of Taxes,  file any material  return or
any amendment to a material return, enter into any closing agreement, settle any
claim or  assessment  in respect of Taxes (except  settlements  effected  solely
through  payment of  immaterial  sums of money),  or consent to any extension or
waiver of the limitation period applicable to any claim or assessment in respect
of Taxes;
                                       -9-
         (x)  write  down or  write  up (or  fail to  write  down or write up in
accordance  with  U.S.  GAAP  consistent  with past  practice)  the value of any
receivables  or revalue any of the  Company's  assets other than in the Ordinary
Course of Business and in accordance with U.S. GAAP;
         (y) issue any purchase orders or otherwise agreed to make any purchases
involving  exchanges in value in excess of Two Thousand Five Hundred Dollars and
Zero Cents  ($2,500.00)  individually  or Five  Thousand  Dollars and Zero Cents
($5,000.00) in the aggregate, except in the Ordinary Course of Business;
         (z) merge with, enter into a consolidation  with or acquire an interest
of 5% or more in any  Person or acquire a  substantial  portion of the assets or
business of any Person or any division or line of business  thereof engaged in a
business  relating to the Operations,  or otherwise  acquire any material assets
relating to the Operations except in the Ordinary Course of Business;
         (aa)  (i)  grant,   announce,  or  make  any  change  in  the  rate  of
compensation,  wages, salaries,  commission,  bonuses,  incentives,  pensions or
other direct or indirect  remuneration or benefits  payable,  or pay or agree or
orally  promised  to pay,  conditionally  or  otherwise,  any bonus,  incentive,
retention  or other  compensation,  retirement,  welfare,  fringe  or  severance
benefit or vacation  pay, to or in respect of any director,  officer,  employee,
distributor,  contractor, or agent of the Company relating to or involved in the
Operations,  including any increase or change pursuant to any Plan or (ii) enter
into,  establish,  increase  or  promise to  increase,  amend or  terminate  any
benefits under any Plan or any  employment or severance  agreement or commitment
or  collective  bargaining  agreement  with any  employee or  contractor  of the
Company  relating  to or involved  in the  Operations,  in either case except as
required by Law or any collective  bargaining  agreement,  such exceptions being
disclosed in the Disclosure Schedules;
         (bb) fail to pay any creditor any material amount owed to such creditor
when due;
         (cc) change in any manner the character or scope of the Operations;
         or
         (dd)  agree,  whether  in  writing  or  otherwise,  to take any  action
described in this Section 4.3 or grant any options to purchase,  rights of first
refusal,  rights of first offer or any other similar rights or commitments  with
respect to any of the actions specified in this Section 4.3, except as expressly
contemplated by this Agreement.
         Section 4.4.  Full Access.
         -------------------------
         The Company shall permit  representatives  of the Optionee to have full
access (upon reasonable  notice and at all reasonable  times, and in a manner so
as not to interfere with the normal  business  operations of the Company) to all
                                       -10-
premises, properties, financial and accounting records, contracts, other records
and  documents,  and  personnel,  of or  pertaining  to the Company,  subject to
compliance with applicable confidentiality obligations of the Company.
         Section 4.5.  Notice of Breaches.
         --------------------------------
         The Company shall  promptly  deliver to the Optionee  written notice of
any event or development of which the Company is aware and that would (a) render
any  statement,  representation  or warranty  of the  Company in this  Agreement
(including  the  Disclosure  Schedule)  inaccurate or incomplete in any material
respect, or (b) constitute or result in a breach by the Company of, or a failure
by the Company to comply  with,  any  agreement  or  covenant in this  Agreement
applicable to such Party.  The Optionee  shall  promptly  deliver to the Company
written  notice of any event or  development of which the Optionee is aware that
would (i) render any  statement,  representation  or warranty of the Optionee in
this  Agreement  inaccurate  or  incomplete  in any  material  respect,  or (ii)
constitute  or  result  in a breach by the  Optionee  of,  or a  failure  by the
Optionee to comply with, any agreement or covenant in this Agreement  applicable
to such  Party.  No such  disclosure  shall be  deemed to avoid or cure any such
misrepresentation or breach.
         Section 4.6.  Exclusivity.
         -------------------------
         The Company  agrees that from the date of execution  of this  Agreement
until the earlier of (a) the Closing Date or (b)  termination  of this Agreement
in  accordance  with Article VI hereof,  the Company  shall not, and the Company
shall use its best efforts to cause each of its officers, directors,  employees,
representatives  and  agents  not  to,  directly  or  indirectly,  (a)  solicit,
initiate,  engage  or  participate  in or  knowingly  encourage  discussions  or
negotiations with any person or entity (other than the Optionee)  concerning any
merger,   consolidation,   sale  of  assets,  tender  offer,   recapitalization,
accumulation  of  stock,  proxy  solicitation  or  other  business   combination
involving  the Company or any  division of the Company,  (b) solicit,  initiate,
entertain or encourage any proposal or offer related to such an acquisition, (c)
provide any non-public information concerning the business, properties or Assets
of the Company to any person or entity  (other than the  Optionee)  or (d) enter
into any  understanding,  letter of  intent or  agreement,  whether  binding  or
non-binding,  in connection  with the foregoing.  The Company shall  immediately
notify the Optionee  of, and shall  disclose to the Optionee all details of, any
inquiries,  discussions  or  negotiations  of the nature  described in the first
sentence of this Section 4.6. The term  "indirectly"  shall include,  but not be
limited to, through Company representatives.
         Section 4.7.  Reasonable Commercial Efforts and Further Assurances.
         ------------------------------------------------------------------
         Each  of  the  Parties  shall  use  reasonable  commercial  efforts  to
effectuate  the  transactions  contemplated  hereby  and to fill and cause to be
fulfilled the  conditions to closing under this  Agreement.  Each Party,  at the
reasonable  request of another  Party,  shall  execute  and  deliver  such other
instruments and do and perform such other acts and things as may be necessary or
desirable for effecting  completely the  consummation  of this Agreement and the
transactions contemplated hereby.
                                       -11-
         Section 4.8.  Funding of Business Plan.
         --------------------------------------
         If the Closing occurs prior to June 30, 2007, absent a Material Adverse
Effect, as determined by and in the sole discretion of Optionee,  Optionee shall
provide  support,  as more fully described in Schedule 4.8, to the Operations to
be  transferred  from Seller to Optionee as provided  herein in order to, in the
reasonable  judgment of Optionee,  enable the Minimum Revenue Trigger to be met.
It is currently  anticipated that such support, if any, will be reflected in the
approval budgets for the Operations to be transferred from Seller to Optionee as
further described in the Supply and Services Agreement.
                                    ARTICLE V
                    CONDITIONS TO CONSUMMATION OF TRANSACTION
         Section 5.1.  Conditions to Each Party's Obligations.
         ----------------------------------------------------
         The  respective  obligations  of  each  Party  to  the  Option  Closing
hereunder are subject to the following conditions:
         (a) The Company shall have received the Requisite  Stockholder Approval
from the stockholders of the Company.
         (b) Any required notice to the Company's  preferred  stockholders shall
have been given or waived; and
         (c)  Subject to the  Requisite  Stockholder  Approval,  Company and the
Optionee shall have entered into the License Agreement.
         Section 5.2.  Conditions to Obligations of the Optionee.
         -------------------------------------------------------
         The  obligation  of the  Optionee to the Option  Closing  hereunder  is
subject to the satisfaction of the following additional conditions:
         (a) the Company  shall have  performed or complied with in all material
respects its agreements and covenants  required to be performed or complied with
under this Agreement as of or prior to the Option Closing;
         (b) the  representations  and  warranties  of the  Company set forth in
Article II shall be true and  correct as of the date  hereof,  and shall be true
and correct as of the Option Closing,  except for representations and warranties
made as of a specific date, which shall be true and correct as of such date;
         (c) the Company  shall have  delivered  to the  Optionee a  certificate
(without  qualification  as to knowledge or  materiality  or  otherwise)  to the
effect  that each of the  conditions  specified  in clauses  (a) and (b) of this
Section 5.2 is satisfied in all respects;
                                       -12-
         (d) The Company shall have received the consent of AngioDynamics, Inc.,
substantially in the form of Exhibit D, attached hereto, to assign the Company's
rights and obligations  under that certain  Distributor  Agreement,  dated as of
June 28, 2002, between the Company and AngioDynamics, Inc.
         (e)  ▇▇▇▇▇ ▇.  ▇▇▇▇▇▇  shall  have  entered  into a  Voting  Agreement,
substantially in the form attached hereto as Exhibit E; and
         (f)  ▇▇▇▇▇  ▇.  ▇▇▇▇▇▇  and the  Company  shall  have  entered  into an
Employment  Agreement  substantially  in the form set forth on Exhibit F hereto;
and
         (g) ▇▇▇▇▇ ▇. ▇▇▇▇▇▇ and the  Optionee  shall have  entered  into a Side
Letter Agreement substantially in the form set forth on Exhibit G hereto.
         Section 5.3.  Conditions to Obligations of the Company.
         ------------------------------------------------------
         The  obligation  of  the  Company  to  consummate  the  Option  Closing
hereunder is subject to the satisfaction of the following additional conditions:
         (a) The Optionee  shall have performed or complied with in all material
respects its agreements and covenants  required to be performed or complied with
under this Agreement as of or prior to the Option Closing;
         (b) the  representations  and  warranties  of the Optionee set forth in
Article III shall be true and correct as of the date  hereof,  and shall be true
and correct as of the Option Closing,  except for representations and warranties
made as of a specific date, which shall be true and correct as of such date; and
         (c) the  Optionee  shall have  delivered  to the Company a  certificate
(without  qualification  as to knowledge or  materiality  or  otherwise)  to the
effect  that each of the  conditions  specified  in  clause  (a) and (b) of this
Section 5.3 is satisfied in all respects.
                                   ARTICLE VI
                                   TERMINATION
         Section 6.1.  Termination of Agreement.
         --------------------------------------
         The Parties may terminate this  Agreement  prior to the Closing Date as
provided below:
         (a) the Parties may terminate this Agreement by mutual written consent;
         (b) any Party may terminate  this Agreement by giving written notice to
the other Parties upon the entry of any permanent injunction or other order of a
court  or  other  competent   authority   preventing  the  consummation  of  the
transaction that has become final and nonappealable;
                                       -13-
         (c) The Optionee may terminate  this Agreement if any of the conditions
set forth in Section 5.1 or 5.2 is not  satisfied  on or prior to  December  17,
2005 and the Optionee is not then in breach of this Agreement;
         (d) the Company may terminate  this  Agreement if any of the conditions
set forth in Section 5.1 or 5.3 are not  satisfied  on or prior to December  17,
2005 and the Company is not then in breach of this Agreement; and
         (e) the Optionee may terminate  this  Agreement for any reason prior to
the Closing Date.
         Section 6.2.  Effect of Termination.
         -----------------------------------
         If any Party  terminates  this  Agreement  pursuant to Section 6.1, all
obligations of the Parties shall terminate without any liability of any Party to
any other Party.  Notwithstanding the foregoing, the following obligations shall
survive  termination of this Agreement:  (i) liability of any Party for breaches
of this Agreement;  (ii) confidentiality,  as provided in Section 7.1; and (iii)
each Party's obligation to bear its own fees and expenses incurred in connection
with the  preparation  and  negotiation of this  Agreement and the  transactions
contemplated herein as provided in Section 7.11.
         Section 6.3.  Amendment.
         -----------------------
         The  Parties  may cause  this  Agreement  to be  amended at any time by
execution of an instrument in writing signed on behalf of each of the Parties.
         Section 6.4.  Extension; Waiver.
         -------------------------------
         At any time prior to the  Closing  Date,  any Party may,  to the extent
legally  allowed  (i)  extend  the  time  for  the  performance  of  any  of the
obligations or other acts of the other Parties;  (ii) waive any  inaccuracies in
the representations and warranties made to such Party contained herein or in any
document  delivered  pursuant hereto and (iii) waive  compliance with any of the
agreements or conditions  for the benefit of such Party  contained  herein.  Any
agreement on the part of a Party to any such  extension or waiver shall be valid
only if set forth in an instrument in writing signed on behalf of such Party.
                                   ARTICLE VII
                                  MISCELLANEOUS
         Section 7.1.  Press Releases and Announcements.
         ----------------------------------------------
         No Party  shall issue any press  release or make any public  disclosure
relating to the subject matter of this  Agreement  without the prior approval of
the  other  Parties;  provided,  however,  that any  Party  may make any  public
disclosure it believes in good faith is required by law or regulation  (in which
case the disclosing Party  shall advise the other Parties and provide them  with
                                       -14-
a  copy  of  the   proposed   disclosure   prior  to  making  the   disclosure).
Notwithstanding  the  foregoing,  the  Parties  acknowledge  that  Optionee is a
reporting  company under the  Securities  Exchange Act of 1934, as amended,  and
will be  required to  publicly  disclose  this  Agreement  and the  transactions
contemplated  hereby in the form of press releases,  Current Reports on Form 8-K
and such other means as Optionee determines.
         Section 7.2.  No Third Party Beneficiaries.
         ------------------------------------------
         This Agreement  shall not confer any rights or remedies upon any person
other than the Parties and their respective successors and permitted assigns.
         Section 7.3.  Entire Agreement.
         ------------------------------
         This Agreement,  the Disclosure Schedule, the Schedules,  the documents
and  instruments  and other  agreements  among the  Parties  referred  to herein
constitute  the entire  agreement  among the  Parties and  supersedes  any prior
understandings,  agreements or representations by or among the Parties,  written
or oral, with respect to the subject matter hereof.
         Section 7.4.  Succession and Assignment.
         ---------------------------------------
         This  Agreement  shall be binding  upon and inure to the benefit of the
Parties and their  respective  successors  and permitted  assigns.  No Party may
assign either this  Agreement or any of its rights,  interests,  or  obligations
hereunder  without the prior  written  approval of the other  Parties,  provided
however,  that  Optionee  may assign  some or all of its rights  hereunder  to a
wholly owned subsidiary.
         Section 7.5.  Counterparts.
         --------------------------
         This  Agreement  may be executed in two or more  counterparts,  each of
which shall be deemed an original but all of which together shall constitute one
and the same instrument.
         Section 7.6.  Headings.
         ----------------------
         The section  headings  contained  in this  Agreement  are  inserted for
convenience  only and shall not affect in any way the meaning or  interpretation
of this Agreement.
         Section 7.7.  Notices.
         ---------------------
         All  notices,  requests,  demands,  claims,  and  other  communications
hereunder  shall be in writing.  Any notice,  request,  demand,  claim, or other
communication  hereunder  shall be deemed duly delivered two business days after
it is sent by registered or certified mail,  return receipt  requested,  postage
prepaid,  or one  business  day  after  it is sent  via a  reputable  nationwide
overnight courier service or sent via facsimile (with acknowledgment of complete
transmission)  with a confirmation copy by registered or certified mail, in each
case to the intended recipient as set forth in the Purchase Agreement.
                                       -15-
         Any  Party  may give  any  notice,  request,  demand,  claim,  or other
communication  hereunder  using any other means  (including  personal  delivery,
expedited  courier,  messenger  service,  telecopy,  telex,  ordinary  mail,  or
electronic  mail),  but  no  such  notice,  request,  demand,  claim,  or  other
communication  shall be  deemed  to have been  duly  given  unless  and until it
actually is received by the Party for whom it is intended.  Any Party may change
the  address  to  which   notices,   requests,   demands,   claims,   and  other
communications  hereunder are to be delivered by giving the other Parties notice
in the manner herein set forth.
         Section 7.8.  Governing Law.
         ---------------------------
         This  Agreement  shall be governed by and construed in accordance  with
the internal laws (and not the law of conflicts) of the State of California.
         Section 7.9.  Amendments and Waivers.
         ------------------------------------
         The Parties may mutually  amend any provision of this  Agreement at any
time prior to Closing  Date.  No  amendment of any  provision of this  Agreement
shall be valid  unless  the same  shall be in  writing  and signed by all of the
Parties. No waiver by any Party of any default,  misrepresentation  or breach of
warranty or covenant  hereunder,  whether intentional or not, shall be deemed to
extend  to any  prior or  subsequent  default,  misrepresentation  or  breach of
warranty or covenant hereunder or affect in any way any rights arising by virtue
of any prior or subsequent default,  misrepresentation,  breach of such warranty
or covenant.
         Section 7.10.  Severability.
         ---------------------------
         Any  term  or   provision  of  this   Agreement   that  is  invalid  or
unenforceable in any situation in any jurisdiction shall not affect the validity
or  enforceability  of the remaining terms and provisions hereof or the validity
or  enforceability  of the offending term or provision in any other situation or
in any  other  jurisdiction.  If the  final  judgment  of a court  of  competent
jurisdiction   declares  that  any  term  or  provision  hereof  is  invalid  or
unenforceable,  the Parties  agree that the court  making the  determination  of
invalidity  or  unenforceability  shall  have the  power to  reduce  the  scope,
duration, or area of the term or provision, to delete specific words or phrases,
or to replace  any invalid or  unenforceable  term or  provision  with a term or
provision that is valid and enforceable and that comes closest to expressing the
intention of the invalid or unenforceable term or provision,  and this Agreement
shall be  enforceable  as so modified  after the  expiration  of the time within
which the judgment may be appealed,  provided that this Agreement shall not then
substantially deprive either Party of the bargained-for performance of the other
Party.
         Section 7.11.  Expenses.
         -----------------------
         All fees and  expenses  (including  all legal and  accounting  fees and
expenses and all other  expenses)  incurred by Optionee in connection  with this
Agreement  and the  transactions  contemplated  hereby shall be paid by Optionee
whether or not the transaction is consummated. All transaction costs incurred by
the Company in connection with this Agreement and the transactions  contemplated
hereby  shall  be  paid  by the  Company  whether  or  not  the  transaction  is
consummated.
                                       -16-
         Section 7.12.  Other Remedies.
         -----------------------------
         Except  as  otherwise  provided  herein,  any and all  remedies  herein
expressly  conferred  upon a  Party  will be  deemed  cumulative  with,  and not
exclusive  of, any other remedy  conferred  hereby or by law or equity upon such
Party,  and the  exercise  by a Party of any one remedy  will not  preclude  the
exercise of any other remedy.
         Section 7.13.  Construction.
         ---------------------------
         The Parties agree that they have been represented by counsel during the
negotiation,  preparation and execution of this Agreement and, therefore,  waive
the  application  of any  law,  regulation,  holding  or  rule  of  construction
providing  that  ambiguities in an agreement or other document will be construed
against the Party  drafting  such  agreement or document.  Any  reference to any
federal,  state,  local, or foreign statute or law shall be deemed also to refer
to all rules and regulations promulgated thereunder, unless the context requires
otherwise.
         Section 7.14.  Incorporation of Schedules and Disclosure Schedule.
         -----------------------------------------------------------------
         The Exhibits,  Schedules  and  Disclosure  Schedule  identified in this
Agreement are incorporated herein by reference and made a part hereof.
                           [Signature page to follow]
                                       -17-
                                                                  EXECUTION COPY
         IN WITNESS WHEREOF,  the parties hereto have executed this Agreement as
of the date first above written.
                                         SURGICA CORPORATION
                                         By:    /s/ ▇▇▇▇▇ ▇. ▇▇▇▇▇▇
                                            ---------------------------------
                                         Name:  ▇▇▇▇▇ ▇. ▇▇▇▇▇▇
                                         Title: President and Chief Executive
                                                 Officer
                                         PROTEIN POLYMER TECHNOLOGIES, INC.
                                         By:    /s/ ▇▇▇▇▇▇▇ ▇. ▇▇▇▇▇▇▇▇▇, III
                                            ---------------------------------
                                         Name:  ▇▇▇▇▇▇▇ ▇. ▇▇▇▇▇▇▇▇▇, III
                                         Title: Chief Executive Officer
             [Signature Page to the Asset Purchase Option Agreement]