EXHIBIT 1
JOINT FILING AGREEMENT
By this Agreement, the undersigned agree that this Statement on Schedule
13D being filed on or about this date, and any subsequent amendments thereto
filed by any of us, with respect to the securities of NeurogesX, Inc. is being
filed on behalf of each of us.
February 22, 2010
▇▇▇▇▇ ▇▇▇▇▇
/s/ ▇▇▇▇▇▇▇▇ ▇▇▇▇▇
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By: ▇▇▇▇▇▇▇▇ ▇▇▇▇▇*
Title: Attorney-in-fact
▇. ▇▇▇▇▇ (1999) LTD.
/s/ ▇▇▇▇▇▇▇▇ ▇▇▇▇▇
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By: ▇▇▇▇▇▇▇▇ ▇▇▇▇▇**
Title: Attorney-in-fact for ▇▇▇▇▇ ▇▇▇▇▇,
Chairman of ▇. ▇▇▇▇▇ (1999) Ltd.
SPHERA FUNDS MANAGEMENT LTD.
/s/ ▇▇▇▇▇ ▇▇▇▇▇▇
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By: ▇▇▇▇▇ ▇▇▇▇▇▇
Title: CEO
ISRAEL MOR
/s/ Israel Mor
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By: Israel Mor
▇▇▇▇▇ ▇▇▇▇▇
/s/ ▇▇▇▇▇ ▇▇▇▇▇
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By: Doron ▇▇▇▇▇
▇▇▇ SENATOR
/s/ ▇▇▇ Senator
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By: ▇▇▇ Senator
* Duly authorized under Special Power of Attorney appointing ▇▇▇▇▇▇▇▇ ▇▇▇▇▇
attorney-in-fact, dated August 12, 2009 by and on behalf of ▇▇▇▇▇ ▇▇▇▇▇
(incorporated herein by reference to Exhibit 2 to the Schedule 13G filed by
▇▇▇▇▇ ▇▇▇▇▇, ▇. ▇▇▇▇▇ (1999) Ltd., Sphera Global Healthcare GP Ltd., Sphera
Global Healthcare Management L.P., Sphera Global Healthcare Fund, and Sphera
Global Healthcare Master Fund on August 13, 2009 (the "Original Schedule 13G)).
** Duly authorized under Special Power of Attorney appointing ▇▇▇▇▇▇▇▇ ▇▇▇▇▇
attorney-in-fact, dated August 12, 2009 by and on behalf of ▇▇▇▇▇ ▇▇▇▇▇ as
Chairman ▇. ▇▇▇▇▇ (1999) Ltd. (incorporated herein by reference to Exhibit 3 to
the Original Schedule 13G).
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