EXHIBIT 10.13
AMENDMENT No. 1 TO RESEARCH
AGREEMENT
This Amendment No. I to Research Agreement ("Amendment") is made and entered
into as of November 20, 2000 by and between B-Twelve, Inc. ("Sponsor") and The
University of Texas M.D. ▇▇▇▇▇▇▇▇ Cancer Center ("Institution"), a component of
the University of Texas System ("System").
RECITALS
A. Sponsor and Institution entered into a Sponsored Research Agreement
dated August 31, 1999 (the "Agreement").
B. Sponsor and Institution wish to amend the terms of the Agreement as set
forth below.
NOW, THEREFORE, it is hereby agreed as follows:
1. Section 2 of the Agreement shall be revised to read in its entirety as
follows:
"In consideration for performance of the Study by Institution, Sponsor
shall pay Institution Eighty four Thousand and no/100 Dollars
(S84,000.00) for Study related costs expenses and other costs. This
amount shall be payable in four quarterly installments in the amount of
Twenty-one Thousand and no/100 Dollars (521,000.00) each. The first
payment has been made. The second payment is payable by December 31,
2000. "
2. Section 3.1 of the Agreement shall be revised to read in its entirety
as follows:
This Agreement shall continue in force until the earlier of completion
of the Study as mutually agreed upon by the parties or until October
31, 2001; provided, however, that either party may terminate the
Agreement by giving thirty (30) days advance notice to the other."
3. Except as expressly provided in this Amendment, all other terms,
conditions and provisions of the Agreement shall continue in full force
and effect as provided therein.
THIS SECTION IS INTENTIONALLY LEFT BLANK.
IN WITNESS WHEREOF, Sponsor and Institution have entered into this Amendment
effective as of the date first set forth above.
B-TWELVE, INC. THE UNIVERSITY OF TEXAS
M.D. ▇▇▇▇▇▇▇▇ CANCER CENTER
By /s/ ▇▇▇ ▇▇▇▇▇▇ By /s/▇▇▇▇▇▇▇ ▇. ▇▇▇▇▇▇▇▇
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▇▇▇ ▇▇▇▇▇▇, M.D., FRCPC ▇▇▇▇▇▇▇ ▇. ▇▇▇▇▇▇▇▇, M.D., M.B.A.
President and CEO Vice President for Research Administration
Date: Nov. 20, 2000 Date: 11/27/00
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I have read this Amendment and understand
my obligations hereunder:
/s/▇▇▇▇▇▇ ▇. ▇▇▇▇▇▇
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▇▇▇▇▇▇ ▇. ▇▇▇▇▇▇, Ph.D.
Principal Investigator
/s/▇▇▇▇▇▇ ▇. ▇▇▇▇▇, M.D.
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▇▇▇▇▇▇ ▇. ▇▇▇▇▇, M.D.
Head Ad Interim, Division of Cancer
Medicine
Reviewed and Approved
/s/▇. ▇▇▇▇▇
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Date: 11-21-00
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