0001047469-15-004216 Sample Contracts

NEPHROGENEX, INC. (a Delaware corporation) [·] Shares of Common Stock UNDERWRITING AGREEMENT
Underwriting Agreement • April 30th, 2015 • NephroGenex, Inc. • Pharmaceutical preparations • New York
SECOND AMENDMENT TO LICENSE AGREEMENT
License Agreement • April 30th, 2015 • NephroGenex, Inc. • Pharmaceutical preparations

This Second Amendment to the License Agreement, effective as of this 16th day of March, 2015 (the “Amendment Date”) by and between NephroGenex, Inc., a Delaware corporation having its principal place of business at 2300 Englert Drive, Durham, NC, 27713 (“LICENSEE”) and Vanderbilt University by and through its Center for Technology Transfer and Commercialization, having a principal place of business at 1207 17th Avenue South, Suite 105, Nashville, TN 37212 (hereinafter referred to as “VANDERBILT”),