0001193125-06-015574 Sample Contracts

NUVELO, INC. 6,500,000 Shares of Common Stock Underwriting Agreement
Underwriting Agreement • January 31st, 2006 • Nuvelo Inc • In vitro & in vivo diagnostic substances • New York

Nuvelo, Inc., a Delaware corporation (the “Company”), proposes to issue and sell to the several Underwriters listed in Schedule 1 hereto (the “Underwriters”), for whom you are acting as representatives (the “Representatives”), an aggregate of 6,500,000 shares of common stock, par value $0.001 per share (the “Common Stock”), of the Company (the “Underwritten Shares”) and, at the option of the Underwriters, up to an additional 975,000 shares of Common Stock (the “Option Shares”). The Underwritten Shares and the Option Shares are herein referred to as the “Shares.”