0001193125-06-065280 Sample Contracts

EXCLUSIVE LICENSE AGREEMENT BETWEEN OHSU AND D-NOVO THERAPEUTICS, INC.
Exclusive License Agreement • March 28th, 2006 • Novacea Inc • Pharmaceutical preparations • Oregon

This Agreement is made and entered into between the Oregon Health & Science University (hereinafter OHSU) having offices at 3181 S. W. Sam Jackson Park Road, Portland, Oregon 97201-3098, and D-Novo Therapeutics, Inc. (hereinafter Licensee), a California corporation having offices at 28202 Cabot Road, Suite 200, Laguna Niguel, California 92677 on this 27th day of June, 2001 (“Effective Date”).

LICENSE AGREEMENT
License Agreement • March 28th, 2006 • Novacea Inc • Pharmaceutical preparations • Pennsylvania

This License Agreement (the “Agreement”) is made and entered into as of the 1st day of July, 2002 (the “Effective Date”), by and between the UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, a non-profit corporation, organized and existing under the laws of the Commonwealth of Pennsylvania, having its principal office at 4200 Fifth Avenue, Pittsburgh, Pennsylvania 15260 (“UNIVERSITY”) and NOVACEA, INC., a Delaware corporation having its primary place of business at 601 Gateway Boulevard, Suite 450, South San Francisco, California 94080 (“LICENSEE”).

ADDENDUM No. 1 to the PATENT AND KNOW-HOW LICENSE AGREEMENT between PIERRE FABRE MEDICAMENT S.A. and NOVACEA, Inc. Dated February 21, 2006
Patent and Know-How License Agreement • March 28th, 2006 • Novacea Inc • Pharmaceutical preparations

This ADDENDUM No. 1 to the Patent and Know-How License Agreement effective as of February 21, 2006 (the “ADDENDUM No. 1 Effective Date”) is executed by and between PIERRE FABRE MEDICAMENT S.A., a corporation organized under the laws of France with headquarters at 45, place Abel-Gance, 92100 BOULOGNE, FRANCE (“PIERRE FABRE”), and, NOVACEA, INC., a Delaware corporation with a principal place of business at 601 Gateway Boulevard, Suite 800, SOUTH SAN FRANCISCO, CALIFORNIA 94080, U.S.A. (“NOVACEA”).

SECOND AMENDMENT TO SUPPLY AGREEMENT
Supply Agreement • March 28th, 2006 • Novacea Inc • Pharmaceutical preparations • New Jersey

THIS SECOND AMENDMENT TO SUPPLY AGREEMENT (the “Amendment”) is dated as of March 21, 2006, by and between Novacea, Inc., a Delaware corporation previously known as D-NOVO Therapeutics, Inc. (“Novacea”) and Plantex USA, Inc., a New Jersey corporation (“Plantex”).