0001558370-25-011671 Sample Contracts

AT THE MARKET OFFERING AGREEMENT August 13, 2025
At the Market Offering Agreement • August 19th, 2025 • ProMIS Neurosciences Inc. • Pharmaceutical preparations • New York

ProMIS Neurosciences Inc., a corporation continued under the Business Corporations Act (Ontario) (the “Company”), confirms its agreement (this “Agreement”) with H.C. Wainwright & Co., LLC (the “Manager”) as follows: