0001564590-21-017811 Sample Contracts

AMENDMENT NO. 1 TO Capital on Demand™ SALES AGREEMENT
Capital on Demand™ Sales Agreement • April 6th, 2021 • ARCA Biopharma, Inc. • In vitro & in vivo diagnostic substances • New York

ARCA biopharma, Inc., a Delaware corporation (the “Company”), together with JonesTrading Institutional Services, Inc. (the “Agent”), are parties to that certain Capital on DemandTM Sales Agreement dated July 22, 2020 (the “Original Agreement”). All capitalized terms not defined herein shall have the meanings ascribed to them in the Original Agreement. The Company and the Agent desire to amend the Original Agreement as set forth in this Amendment No. 1 thereto (this “Amendment) as follows: