Validated Target definition

Validated Target means a Target that has been validated in vitro ---------------- or in vivo as part of a TVD program by ATUGEN or its Collaborator.
View Source
Validated Target means a biological drug target against which any drug has received Marketing Authorization Approval.
View Source
Validated Target means a Target which has been shown to meet all of the following criteria approved by the PC: (a) the Target is well characterized (i.e., its biochemical and physiological actions are reasonably well understood); (b) agents, ligands, or intracellular molecules that interact with the Target demonstrate a desired effect on a biological process in relationship to a disease state or disorder; and (c) the Target is shown to be present in human tissue with the disease state or condition.
View Source

Examples of Validated Target in a sentence

  • Rigel shall notify the CMC in writing of each Novel Validated Target identified by Rigel during the Research Period of each Joint Project promptly after its identification.

  • At any time during the Exclusivity Term with respect to a Novel Validated Target, Novartis shall on a not less than quarterly basis provide documentation to the reasonable satisfaction of Rigel that Novartis is maintaining a diligent, continuous program with respect to the Novel Validated Target.

  • At any time during the Exclusivity Term with respect to a Novel Validated Target, Novartis, at its sole discretion, may request in writing that Rigel conduct Compound Screening of Rigel's small-molecule compound library against such Novel Validated Target.

  • The date on which Rigel has delivered the notice described in this Section 4.1.4, provided Novartis has not within ten (10) business days of receipt of said notice informed Rigel that in Novartis' opinion, the CMC-predetermined validation cirteria have not been met, shall be considered the "Notice Date" of such Novel Validated Target.

  • Novartis shall have the right to initiate Compound Screening with each Novel Validated Target upon notice to Rigel any time during the Exclusivity Term with respect to such Novel Validated Target.


More Definitions of Validated Target

Validated Target means any one or more of the following: (i) NMDA channels, (ii) sodium channels, and/or (iii) both NMDA and sodium channels, if so designated by the Research Management Committee pursuant to Section 4.1, or other glutamate-activated channels that the Research Management Committee determines from time to time.
View Source
Validated Target means the *** .
View Source
Validated Target means a Target which has been shown to meet all of the following criteria approved by the PC: (a) the Target is well characterized (i.e., its biochemical and physiological actions are reasonably well understood); (b) agents, ligands, or intracellular molecules that interact with the Target demonstrate a desired effect on a biological process in relationship to a disease state or disorder; and (c) the Target is shown to be present in human tissue with the disease state or condition. ARTICLE II -
View Source
Validated Target means a biological molecule (e.g., receptor, enzyme, ion channel or protein domain) or Gene, the function of which has been identified and which has been determined by the Management Committee to be potentially useful in the discovery of a Drug. As used in this Agreement, the following terms shall have the respective meanings specified in the Sections indicated below. Section -------
View Source
Validated Target means a Target which has been shown to meet all of the following criteria approved by the PC: (a) the Target is well characterized (i.e., its biochemical and physiological actions are reasonably well understood); (b) agents, ligands, or intracellular molecules that interact with the Target demonstrate a desired effect on a biological process in relationship to a disease state or disorder; and (c) the Target is shown to be present in human tissue with the disease state or condition. ARTICLE II - TERMINATION OF THE MULTI-PROJECT COLLABORATION AGREEMENT AND OVERVIEW AND MANAGEMENT OF COLLABORATION
View Source
Validated Target means a Receptor target that has been shown to be correlated with a particular disease in which a small molecule therapeutic would offer a reasonable commercial opportunity, and where inhibition of target function in in vitro and in vivo models leads to effective inhibition of pathophysiology.
View Source
Validated Target means a biological molecule which is the subject of a Decision that such biological molecule is [CONFIDENTIAL TREATMENT REQUESTED].
View Source