Central ECHO imaging readings Sample Clauses

Central ECHO imaging readings. The primary goal is to read the wall motion at rest and to assess the wall motion abnormalities induced during the stress protocol. Wall motion abnormalities will be graded and scored as defined in the guidelines prepared as for Task 3.1. Besides the conventional stress echocardiographic parameters of regional function such as rest WMSI, and peak WMSI, their variation expressed by the delta WMSI, global function parameters will also be evaluated at rest and at peak stress: ejection fraction (measured by the ▇▇▇▇▇▇▇'▇ rule), end-systolic and end-diastolic volumes. On the basis these parameters it will be possible to provide indexes of global contractility during stress echocardiography (i.e. Bombardini T, et al.. Force-frequency relationship in the echocardiography laboratory: a noninvasive assessment of Bowditch treppe? J Am Soc Echocardiogr. 2003 Jun;16(6):646-55). In a subpopulation transthoracic assessment of proximal coronary flow and flow reserve at baseline and during stress will also be performed. Such data will be included in the analysis where available as a secondary endpoint.

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