Initial Research Plan Clause Samples

Initial Research Plan. The initial Research Plan, which covers the Research Program during Contract Year One, is attached as EXHIBIT 1.45. The Parties acknowledge and agree that such initial Research Plan sets forth the goals and objectives of the Research Program and the broad terms of the Parties' respective undertakings to achieve those goals and objectives. The Parties further acknowledge and agree that the Research Plan will be supplemented and otherwise amended by the JRC from time to time during the Research Term for each stage of the Research Program to identify and define the specific undertakings of the Parties required to implement the Research Program.

Initial Research Plan. An outline of the Research Plan for the Research Collaboration is attached hereto as Exhibit 1.224. Promptly following the Amendment Date, the JRDC shall prepare the initial Research Plan for review and approval by the JSC in accordance with Section 4.4.1, which plan shall include: (a) the activities that Tango will undertake to: (i) develop and finalize the Research Plan Screens, (ii) identify and evaluate proposed screen hits using the Research Plan Screens, (iii) develop a list of proposed screen hits based on initial pre-validation screening utilizing Research Plan Screens, (iv) determine which such proposed screen hits, if any, are to be deemed Screen Hits and (v) validate certain Screen Hits (provided, that Tango shall not be obligated to simultaneously conduct validation activities with respect to more than [***] Targets, unless otherwise agreed by the Parties); and (b) the criteria for validation of such Screen Hits (the “Target Validation Criteria”), which shall be consistent with the baseline criteria set forth in Exhibit 1.224 (the “Baseline Criteria”), unless otherwise agreed by the Parties.

Initial Research Plan. The initial Research Plan, which covers the Research Program during Contract Year One, is attached as EXHIBIT 1.45. The Parties acknowledge and agree that such initial Research Plan sets forth the goals and objectives of the Research Program and the broad terms of the Parties' respective undertakings to achieve those goals and objectives. The Parties further acknowledge and agree that the Research Plan will be supplemented and otherwise amended by the JRC from time to time during the Research Term * Certain information on this page has been omitted and filed separately with the Commission. Confidential treatment has been requested with respect to the omitted portions. AZ AND CK CONFIDENTIAL for each stage of the Research Program to identify and define the specific undertakings of the Parties required to implement the Research Program.

Initial Research Plan. The initial Research Plan for the initial Product covering the period from the Effective Date through the [***] of the [***] is part of the Initial R&D Plan. The Initial R&D Plan, and any amendments thereto, will be divided into pre-defined work packages. The Initial R&D Plan as agreed by the Parties is based on the [***] for development of a Product with a [***] including [***] of such Product with a [***] in an [***] .. Prior to the Effective Date both Parties have [***] other [***] for [***] including a [***] to [***] and/or a Product [***] a [***] . In the Initial R&D Plan certain decision points are included at which the respective JPT shall decide on the above mentioned [***] and may eventually propose amendments of the then-current Research Plan or Development Plan to the JSC for approval. During the performance of the Research Plan, the JRPT will periodically review and propose amendments to the Research Plan, for approval by the JSC, to reflect the progress achieved and the further development activities to be undertaken by the Parties in the research of potential Product candidates, but not less than once every year in conjunction with the required resources and program review cycle. In addition, BI may request that Micromet perform additional research activities that BI believes are [***] in support of [***] for the Product, and Micromet will use reasonable efforts to perform such activities under the Research Plan subject to the availability of resources to perform such activities and the terms of Section 3.3. The Parties agree that, as of the Effective Date, the Initial R&D Plan includes the [***] that the Parties anticipate will be necessary for the [***] of a [***] .. Nevertheless, each Party acknowledges and agrees that the research program described in the Initial R&D Plan is subject to various technical and scientific risks, and that neither Party guarantees that any [***] will result from the performance of such program. *** Certain confidential information contained in this document, marked by brackets, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 of the Securities Exchange Act of 1934, as amended.

Initial Research Plan. Capitalized terms used without definition in this Initial Research Plan have the meanings provided in the Agreement. Confidential Materials omitted and filed separately with the Securities and Exchange Commission. A total of 5 pages were omitted. [**]

Initial Research Plan. From time to time during the Term, Affini-T may draft and propose to the JSC and the JSC shall promptly ([***]) upon receipt of such proposal, consider and subject to Section 3.5, approve research plan(s) for Gene Edits describing the applicable Metagenomi Research Activities (each, a “Research Plan”). As of the Effective Date, the Parties have agreed to the Research Plan for [***] attached hereto as Schedule 4.1. Each Research Plan will include a description of all Metagenomi Research Activities to be performed thereunder, a budget for the conduct of such Metagenomi Research Activities (“Plan Budget”), a timeline for Metagenomi’s performance, key milestones and progress/data/discovery reporting requirements, deliverables, one or more success criteria with respect to such Research Plan and the required contents of the final report and data package to be delivered to Affini-T upon completion of the Research Plan (the “Data Package”).