Common use of Nanopore Extensions Clause in Contracts

Nanopore Extensions. The Flow Cells will be delivered with pre-loaded nanopores, membranes (that hold the nanopores) and electrochemistry on top of a modified chip surface. None of these components either individually or collectively are allowed to be modified, derivativised, replaced or removed. The Sequencing Kits will include other components: enzymes and adaptors that enable sample preparation methods, molecular ‘tethers’ that enable improved analyte to nanopore binding through interactions with the membranes, enzymes that allow for controlled transport of analytes through nanopores, buffered solutions for improved ionic conductance, solutions for washing the Flow Cells between samples and other components as provided by Oxford from time to time. Customer may not analyse, modify or reverse engineer these components, but may develop and use alternative versions (“Nanopore Chemistries”). In addition, Customer is encouraged to develop and use: (a) new application protocols, (b) sample preparation methods, (c) data analysis tools, such as, software written to APIs (application programming interfaces) published by Oxford (but not the Software itself) and/or (d) new uses of the Goods or Software (“Nanopore Extensions”). Customer’s right to create and use Nanopore Extensions and Nanopore Chemistries is conditioned on Customer’s compliance with the Nanopore Extension Requirements. “Nanopore Extension Requirements” means: (i) all titles and trademarks, copyright, patent marking and restricted rights notices are reproduced on any materials embodying Nanopore Extensions or Nanopore Chemistries; (ii) any materials embodying Nanopore Extensions or Nanopore Chemistries must carry prominent notices stating that Customer modified it, and giving a relevant date and that the Nanopore Extension or Nanopore Chemistry must be used only with a Flow Cell; (iii) use of the Nanopore Extension and/or Nanopore Chemistry may not be conditioned on payment of a license fee (or consideration) for use of same; (iv) the Nanopore Extension or Nanopore Chemistry may not be disclosed to or used by any of Oxford’s competitors and Customer may not authorise any of Oxford’s competitors to use the Nanopore Extension or Nanopore Chemistry; (iv) any Nanopore Extension or Nanopore Chemistry is made available under terms and conditions that provide that the Nanopore Extension and/or Nanopore Chemistry is provided “AS IS” and (v) with respect to any Nanopore Extension or Nanopore Chemistry created pursuant to this Section 2.3.4, use is limited to Research Use. Notwithstanding anything herein to the contrary, the Goods or Software may not be used for the development of any other product or service that competes or could compete with the products or services of Oxford.

Nanopore Extensions. The Flow Cells will be delivered with pre-loaded nanopores, membranes (that hold the nanopores) and electrochemistry on top of a modified chip surface. None of these components either individually or collectively are allowed to be modified, derivativised, replaced or removed. The Sequencing Kits will include other components: enzymes and adaptors that enable sample preparation methods, molecular ‘tethers’ that enable improved analyte to nanopore binding through interactions with the membranes, enzymes that allow for controlled transport of analytes through nanopores, buffered solutions for improved ionic conductance, solutions for washing the Flow Cells between samples and other components as provided by Oxford from time to time. Customer may not analyse, modify or reverse engineer these components, but may develop and use alternative versions (“Nanopore Chemistries”). In addition, Customer is encouraged to develop and use: (ai) new application protocols, , (bii) sample preparation methods, (ciii) data analysis tools, such as, software written to APIs (application programming interfaces) published by Oxford (but not the Software itself) and/or (div) new uses of the Goods or Software (“Nanopore Extensions”). Customer’s right to create and use Nanopore Extensions and Nanopore Chemistries is conditioned on Customer’s compliance with the Nanopore Extension Requirements. “Nanopore Extension Requirements” means: (iA) all titles and trademarks, copyright, patent marking and restricted rights notices are reproduced on any materials embodying Nanopore Extensions or Nanopore Chemistries; (iiB) any materials embodying Nanopore Extensions or Nanopore Chemistries must carry prominent notices stating that Customer modified it, and giving a relevant date and that the Nanopore Extension or Nanopore Chemistry must be used only with a Flow Cell; (iiiC) use of the Nanopore Extension and/or Nanopore Chemistry may not be conditioned on payment of a license fee (or consideration) for use of same; (ivD) the Nanopore Extension or Nanopore Chemistry may not be disclosed to or used by any of Oxford’s competitors and Customer may not authorise any of Oxford’s competitors to use the Nanopore Extension or Nanopore Chemistry; (ivE) any Nanopore Extension or Nanopore Chemistry is made available under terms and conditions that provide that the Nanopore Extension and/or Nanopore Chemistry is provided “AS IS” and (vF) with respect to any Nanopore Extension or Nanopore Chemistry created pursuant to this Section 2.3.42.2.4, use is limited to Research Use. Notwithstanding anything herein to the contrary, the Goods or Software may not be used for the development of any other product or service that competes or could compete with the products or services of Oxford.