Common use of Object and Purpose of the Clause in Contracts

Object and Purpose of the. Contract The subject of this Contract is a performance of the Clinical Trial titled “A phase III, randomized, open-label, active-controlled, multicenter study evaluating the efficacy and safety of crovalimab versus eculizumab in adult and adolescent patients with paroxysmal nocturnal hemoglobinuria (PNH) currently treated with complement inhibitors”, ▇▇▇▇▇▇▇▇ ▇▇. ▇▇▇▇▇▇▇, hereinafter referred to as the ‘Study’. 2. The objective of this Contract is to stipulate conditions for conducting the Study and to stipulate rights and obligations of Contract parties regarding conduct of the Study and processing its results. 3. IQVIA and Sponsor hereby appoint the Institution and Principal Investigator to conduct the Study, and the Institution agrees to ensure that the Institution and the Institution’s employees, agents, and staff will conduct the Study in accordance with the Protocol (as may be amended by Sponsor), the terms of this Contract and any other the attachments hereto, which all are incorporated by reference herein (the “Contract”), good clinical practice, and all applicable laws and regulations.

Object and Purpose of the. Contract The subject of this Contract is a performance of the Clinical Trial titled “A phase IIIMULTICENTER, randomizedSINGLE-ARM, openOPEN-labelLABEL, activeEXTENSION, ROLLOVER STUDY TO EVALUATE THE LONG-controlled, multicenter study evaluating the efficacy and safety of crovalimab versus eculizumab in adult and adolescent patients with paroxysmal nocturnal hemoglobinuria (PNH) currently treated with complement inhibitors”, ▇▇▇▇▇▇▇▇ ▇▇TERM SAFETY AND EFFICACY OF OCRELIZUMAB IN PATIENTS WITH MULTIPLE SCLEROSIS,” Protocol No. ▇▇▇▇▇▇▇MN43964, hereinafter referred to as the ‘Study’. 2. The objective of this Contract is to stipulate conditions for conducting the Study and to stipulate rights and obligations of Contract parties regarding conduct of the Study and processing its results. 3. IQVIA and Sponsor hereby appoint the Institution and Principal Investigator to conduct the Study, and the Institution agrees to ensure that the Institution and the Institution’s employees, agents, and staff will conduct the Study in accordance with the Protocol (as may be amended by Sponsor), the terms of this Contract and any other the attachments hereto, which all are incorporated by reference herein (the “Contract”), good clinical practice, and all applicable laws and regulations.