Prototype Design. This instrument will be composed of 13 1 various subsystems: optical, sample delivery, electronics, data acquisition and automated control. At this stage , these subsystems will be designed in accordance to the molecular biology protocols developed in Phase I. Each component will be specified. 2 Constuction of optical subsystem. The 14 3 high-collection-efficiency fluorescence detection optical subsystem will be constructed. This subsystem consists of excitation componenets (laser, focusing optics), fluorescence collection optical components, spectral and spatial discrimination components, and single-photom detection components, in accordance to established single- molecule detection technology. Sequentially numbered page 104
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Sources: Funds in Agreement (Centrex Inc), Funds in Agreement (Centrex Inc)