Common use of SCOPE AND MANAGEMENT OF THE COLLABORATION Clause in Contracts

SCOPE AND MANAGEMENT OF THE COLLABORATION. 2.1 Research activities Conduct INTERCEPT shall conduct research activities (such activities to include but not be limited to synthetic, computational and analytical chemistry) to discover, identify, optimize and/or develop Compounds/Products up to the stage where they fulfil the criteria for a Selected Preclinical Compound. The research activities to be undertaken by INTERCEPT and the various criteria to move from one stage to the other are set forth in the Research Program. The Research Program shall be for an initial period of one year starting upon the Effective Date with a potential extension by way of an amendment to the Agreement of one or several additional year(s) (hereinafter the “Research Program Term”). INTERCEPT will make such contributions in terms of manpower deployment, equipment, facilities, and other contributions as specified in the Research Program. In terms of manpower, it is intended that INTERCEPT will allocate for the performance of the research activities: up to [***] full time equivalent (“FTE”) [***], [***] FTE [***] and [***] FTE [***]. SERVIER will contribute to the financing of the research activities by reimbursing to INTERCEPT at an agreed initial annual rate of EUR [***] per FTE, up to a maximum amount of [***] euros (EUR [***]) per year, provided such costs are duly justified and are in accordance with the budget contained in the Research Program. Such reimbursement will be on a quarterly basis. page 10 of 67 Portions of this Exhibit, indicated by the ▇▇▇▇ “[***],” were omitted and have been filed separately with the Secretary of the Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 406 of the Securities Act of 1933, as amended. INTERCEPT shall exercise Commercially Reasonable Efforts in the performance of the research activities in accordance with the agreed scope of works and timelines specified in the Research Program.

SCOPE AND MANAGEMENT OF THE COLLABORATION. 2.1 Research activities Conduct INTERCEPT shall conduct research activities (such activities to include but not be limited to synthetic, computational and analytical chemistry) to discover, identify, optimize and/or develop Compounds/Products up to the stage where they fulfil the criteria for a Selected Preclinical Compound. The research activities to be undertaken by INTERCEPT and the various criteria to move from one stage to the other are set forth in the Research Program. The Research Program shall be for an initial period of one year starting upon the Effective Date with a potential extension by way of an amendment to the Agreement of one or several additional year(s) (hereinafter the “Research Program Term”). INTERCEPT will make such contributions in terms of manpower deployment, equipment, facilities, and other contributions as specified in the Research Program. In terms of manpower, it is intended that INTERCEPT will allocate for the performance of the research activities: up to [***] full time equivalent (“FTE”) [***], [***] FTE [***] and [***] FTE [***]. SERVIER will contribute to the financing of the research activities by reimbursing to INTERCEPT at an agreed initial annual rate of EUR [***] per FTE, up to a maximum amount of [***] euros (EUR [***]) per year, provided such costs are duly justified and are in accordance with the budget contained in the Research Program. Such reimbursement will be on a quarterly basis. page 10 of 67 Portions of this Exhibit, indicated by the ▇m▇▇▇ “[***],” were omitted and have been filed separately with the Secretary of the Commission pursuant to the Registrant’s application requesting confidential treatment pursuant to Rule 406 of the Securities Act of 1933, as amended. INTERCEPT shall exercise Commercially Reasonable Efforts in the performance of the research activities in accordance with the agreed scope of works and timelines specified in the Research Program.