Common use of True-Up Payment Clause in Contracts

True-Up Payment. The Parties agree that clinical data from any Joint Global Trial will not be subject to a Buy-In Right Payment obligation under Section 9.3(d), except that, notwithstanding Hutchmed’s rights pursuant to Section 2.1 or Hutchmed’s access rights pursuant to Sections 2.6(a), 2.7(a) or 5.3, if Hutchmed or other Hutchmed Entities participate in a Joint Global Trial but do not enroll and treat in the Territory twenty percent (20%) of the total number of patients enrolled or treated globally, then upon completion of such Joint Global Trial, Hutchmed will not have the right to access or use or right of reference to the clinical data or Epizyme Regulatory Documents arising out of such Joint Global Trial unless and until Hutchmed pays Epizyme an amount equal to the product of (i) twenty percent (20%) less the quotient of (A) the total number of patients enrolled and treated in such Joint Global Trial in the Territory divided by (B) the total number of patients enrolled and treated globally in such Joint Global Trial (including such patients enrolled and treated in the Territory), multiplied by (ii) Epizyme’s and Epizyme Entities’ internal costs and Out-of-Pocket Costs incurred in the performance of such Joint Global Trial on a worldwide basis, and (iii) [**] percent ([**]%) (the “True-Up Payment”). Upon receipt of the True-Up Payment from Hutchmed, all such Regulatory Documents from such Joint Global Trial shall automatically become Epizyme Regulatory Documents, all such clinical data from such Joint Global Trial shall automatically become Epizyme Product Data, and all other Know-How arising out of such Joint Global Trial shall automatically become Epizyme Know-How. For clarity, at all times, safety data from both within and outside the Territory shall be shared by the Parties under this Agreement and the Safety Data Exchange Agreement at no cost to the recipient Party in order to fulfill regulatory requirements. Epizyme shall invoice Hutchmed for any True-Up Payment and Hutchmed shall pay such amount within [**] after receipt of the invoice. By way of example and not limitation, if the following figures apply to a Joint Global Trial, then the True-Up Payment shall be $[**]. [**]