Subscription, Joint Development and Operating Agreement Sample Contracts

BETWEEN
Subscription, Joint Development and Operating Agreement • July 17th, 2003 • Generex Biotechnology Corp • Pharmaceutical preparations • New York
AND
Subscription, Joint Development and Operating Agreement • August 4th, 1999 • Targeted Genetics Corp /Wa/ • Biological products, (no disgnostic substances) • New York
AMENDED AND RESTATED SUBSCRIPTION, JOINT DEVELOPMENT AND OPERATING AGREEMENT ELAN CORPORATION, PLC ELAN INTERNATIONAL SERVICES, LTD. ISIS PHARMACEUTICALS, INC. AND ORASENSE LTD. October 24, 2002
Subscription, Joint Development and Operating Agreement • November 20th, 2002 • Isis Pharmaceuticals Inc • Pharmaceutical preparations • New York

The Shares will be issued under an exemption or exemptions from registration under the Securities Act. Accordingly, the certificates evidencing the Shares shall, upon issuance, contain the following legend: