Number of Substitute Targets Clause Samples

Number of Substitute Targets. Notwithstanding anything to the contrary contained in this Agreement, in no event shall the JSC (or AstraZeneca) have the right to designate more than a total of three Substitute Targets under this Section 3.4.3 unless otherwise agreed in writing by the Parties, which agreement may include additional payments to be made by AstraZeneca to Regulus to fund such research and development activities relating to such additional Substitute Target, and may include an extension of the Research Term to allow further time for such addition activities if agreed in writing by the Parties. For clarity, the JSC shall have the right to apply such three rights of substitution to whichever Collaboration Target it wishes. For example, subject to the terms of this Section 3.4.3, the JSC shall have the right to substitute a single Collaboration Target three times, or shall have the right to substitute each Collaboration Target one time (for a total of three substitutes). In no event shall the JSC have the right to designate more than three Substitute Target.